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Classification of capillary damage in patients with type 2 diabetes mellitus: Clinical parameters obtained through capillaroscopy-A cross-sectional study.
Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Type 2 Diabetes Mellitus and Chronic Venous Disease of the Lower Extremities: A Narrative Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Review
- Nailfold Videocapillaroscopy in Pediatric Rheumatology: Established Roles, Emerging Applications, and Future Perspectives.Balkan medical journal · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveDiabetes mellitus (DM) significantly affects microcirculation, leading to microvascular abnormalities that can result in severe systemic complications. Capillaroscopy is a non-invasive and painless method for observing capillary microvasculature, allowing for the assessment of microcirculatory damage. While it is known primarily for its application in rheumatic diseases, recent studies have emphasized its importance in non-rheumatic conditions, such as DM. This growing relevance has led to the aim of developing a classification system for capillary damage in diabetic patients.MethodsCross-sectional study. Eighty randomly selected patients with type 2 diabetes mellitus (T2DM) were evaluated using capillaroscopy to assess capillary damage and establish a classification system.ResultsCapillary damage was observed in all participants (100%), with greater severity associated with longer diabetes duration. Patients were categorized based on the severity of their damage.ConclusionsThe classification system identified three degrees of capillary damage: an early grade, which can be subdivided into initial or established; an intermediate grade, which can also be initial or established (both treatable for potential reversibility); and an advanced grade, which appears to be irreversible. This classification aids in better understanding and managing microvascular damage in diabetic patients.
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