Evidence map›Paper›PMID 41406064›Full record

ArticleOphthalmic research2026

Changes of Schlemm's Canal and Trabecular Meshwork Dimensions from Digital Ocular Massage in High Myopia: A Pilot Study.

Andrew K C Lam, Ruby W L Wong, Tiffany H Y Wu, Henry K C Lau, Carmelo H T Lai, Antonia K W Wong

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Article in Ophthalmic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Andrew K C LamSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China, andrew.kc.lam@polyu.edu.hk.
Ruby W L WongSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Tiffany H Y WuSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Henry K C LauSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Carmelo H T LaiSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Antonia K W WongSchool of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study evaluated changes of Schlemm's canal (SC) and trabecular meshwork (TM) dimensions from digital ocular massage in high myopia.

methodsHealthy participants with either high myopes (≤-6.00 D) or with refractive errors ≥ -3.00D were recruited. Right eyes underwent digital ocular massage. Intraocular pressure (IOP) was monitored using rebound tonometry. Anterior chamber angle was imaged using swept-source optical coherence tomography. IOP, SC, and TM were compared before and immediately after digital ocular massage.

resultsSixteen eyes from 16 high myopes (-6.00 D to -8.125 D) and 18 eyes from 18 control participants (+0.50 D to -2.875 D) were included. There was no difference in age and gender distribution between the two groups. The two groups shared similar IOP, SC area, SC length, TM length, and TM thickness at baseline. Both groups had significant IOP drop from a baseline of around 15 mm Hg to 9 mm Hg after ocular massage. High myopia demonstrated a mild enlargement of the SC area (from 10,655.60 ± 4,362.02 µm2 to 12,632.40 ± 4,393.19 µm2, p = 0.098), not reaching statistical significance. The TM thickness was reduced from 160.21 ± 26.29 µm to 151.77 ± 26.91 µm, p = 0.018). Control eyes showed significant enlargement of SC area (from 8,540.71 ± 3,905.98 µm2 to 11,686.53 ± 4,586.37 µm2, p = 0.001) and SC length (from 240.47 ± 69.96 µm to 280.40 ± 59.37 µm, p = 0.041).

conclusionControl eyes showed significant enlargement of SC in responding to IOP drop while high myopia did not.

Indexed as

Intraocular PressureMassageMyopiaMyopia, DegenerativeTrabecular MeshworkAdultFemaleHumansMaleMiddle AgedPilot ProjectsSchlemm's CanalTomography, Optical CoherenceTonometry, OcularYoung AdultHigh myopiaIntraocular pressureOcular massageSchlemm’s canalTrabecular meshwork

Identifiers

PMID41406064
PMCPMC12829996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.