Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
R Kijoon Kim *Department of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.
Corinne Smith *Department of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.ORCID 0000-0002-0541-2296
Natalie L TrubyDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.ORCID 0000-0001-6891-6654
Shelbey R StrandbergDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.
Jessica L BellDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.ORCID 0000-0001-9563-0125
Nic CarwileDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.ORCID 0009-0000-5767-3300
Gabriella M SilvaDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.
Rachael L NeveGene Delivery Technology Core, Massachusetts General Hospital, Boston, MA 02145.
Theingi AungDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.
Xiaohong CuiDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.
Peter J HamiltonDepartment of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA 23298.ORCID 0000-0002-6819-8346
Funding
VCU Center for Drug Addiction ResearchP30DA033934 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ARON H LICHTMAN · 2014 to 2026
$13.8M
Cell type transcriptional mechanisms of polysubstance choiceR01DA058958 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew L Banks, Peter James Hamilton · 2023 to 2026
$1.8M
Reprogramming KZFP function to understand drug-specific transcription and behaviorR01DA058089 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Peter James Hamilton · 2024 to 2026
$1.5M
Pharmacology of Stimulant ChoiceR01DA055825 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew L Banks, Jose Miguel Eltit · 2023 to 2026
$1.4M
Using CRISPR tools to uncover the role of CREB-gene regulation in drug abuseR00DA045795 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI HAMILTON, PETER JAMES · 2020 to 2022
$739k
Neurocognitive, genetic and socioenvironmental influences on a developmental precursors to addiction: A cross-species studyR34DA061267 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI BANKS, MATTHEW L, BOUNTRESS, KAITLIN ELIZABETH · 2024 to 2025
$689k
Reprogramming Transcription Factors to Study Social BehaviorF31MH133309 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI TRUBY, NATALIE L · 2023 to 2024
$86k
HHS | NIH | National Institute of Mental Health (NIMH) F31MH133309HHS | NIH | National Institute on Drug Abuse (NIDA) P30DA033934HHS | NIH | National Institute on Drug Abuse (NIDA) R00DA045795HHS | NIH | National Institute on Drug Abuse (NIDA) R01DA058089HHS | NIH | National Institute on Drug Abuse (NIDA) R01DA058958HHS | NIH | National Institute on Drug Abuse (NIDA) R34DA061267NIDA NIH HHS P30 DA033934NIDA NIH HHS R00 DA045795NIDA NIH HHS R01 DA055825NIDA NIH HHS R01 DA058089NIDA NIH HHS R01 DA058958NIDA NIH HHS R34 DA061267NIMH NIH HHS F31 MH133309VCU | School of Medicine, Virginia Commonwealth University (VCU Med School) Blick Scholars fundVCU | School of Medicine, Virginia Commonwealth University (VCU Med School) V30 training award from the VCU MD-PhD Enrichment Fund
6 · The paper itself
Abstract
The neurobiological origins of social behaviors are poorly understood. Previous studies have linked the function of a single Krüppel-associated box zinc finger protein (KZFP), ZFP189, in the mouse prefrontal cortex (PFC), with the regulation of transposable elements (TEs), immune genes, and social behaviors. Here, we expand the scope of inquiry to explore the relationship between collective PFC KZFP function and social behaviors by altering the function of the cognate KZFP interacting protein TRIM28 within the PFC of male and female mice. We reprogrammed natural TRIM28
Indexed as
DNA Transposable ElementsPrefrontal CortexSocial BehaviorTripartite Motif-Containing Protein 28AnimalsBehavior, AnimalFemaleMaleMiceMice, Inbred C57BLDNA Transposable ElementsTrim28 protein, mouseTripartite Motif-Containing Protein 28prefrontal cortexsocial behaviortransposable elementsTRIM28
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Derepression of transposable elements in the mouse prefrontal cortex disrupts social behavior. · full record | OpenQuestion