In one paragraphSynthesis in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Pascal DjiadeuSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0000-0001-9708-6530 Housne BegumSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0000-0003-1561-9423 Michelle HaavaldsrudSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada. michelle.haavaldsrud@phac-aspc.gc.ca.ORCID http://orcid.org/0009-0004-8378-9082 Giovanna BusaSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0003-2173-488X Jeffery DansohSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0002-6022-4455 Phu Van NguyenSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0002-0462-4040 Annie FleurantSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0003-6185-7227 Stephan GadientSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0004-4703-7131 Chris ArchibaldSexually Transmitted and Blood Borne Infections Surveillance Division, Centre for Communicable Diseases and Infection Control, Infectious Diseases and Vaccination Programs Branch, Public Health Agency of Canada, 130 Colonnade Rd., Ottawa, ON, K1A 0K9, Canada.ORCID http://orcid.org/0009-0000-9460-980X Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
The risk of sexual transmission of HIV in serodiscordant couples when the partner living with HIV (PLHIV) uses antiretroviral therapy (ART) and maintains a suppressed viral load (VL) (< 200 copies/mL) is estimated at 0.00 transmissions per 100 person-years (95% CI 0.00-0.10). A recent review reported an almost zero transmission risk for VL < 1000 copies/mL but lacked quantitative risk estimates. This systematic review aimed to quantify transmission risk across VL levels. A literature search (November 2023, updated January 2025) identified 152 studies, with 9 included in the analysis. Seven possible transmissions occurred when the PLHIV had a VL of < 1000 copies/mL at the last measurement before the estimated time of transmission. However, VL at the exact time of transmission was unknown and VL > 1000 copies/mL cannot be excluded. This review suggests sexual transmission is very rare with recent VL < 1000 copies/mL however, future research is required to establish precise risk estimates.PROSPERO Number: CRD42023476946.
Indexed as
Anti-HIV AgentsAnti-Retroviral AgentsHIV InfectionsSexual PartnersViral LoadFamily CharacteristicsFemaleHumansMaleRisk FactorsAnti-HIV AgentsAnti-Retroviral Agents< 1000 copies/mLAntiretroviralsEpidemiologyHIV and AIDSHIV transmissionPublic healthSerodiscordant couplesSexually transmitted diseasesSystematic reviewViral load suppression
Identifiers
PMID41405752
PMCPMC13167889
What OpenQuestion holds
Textmetadata
LicenceCC BY
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