ArticleEJNMMI physics2025
Voxel-based dosimetry for predicting treatment response to transarterial radioembolization in hepatocellular carcinoma: significance of intratumoral dose distribution.
Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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6 authors.
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Abstract
purposeWe applied a voxel-based personalized dosimetry method using multiple voxel S-values (VSVs) to assess the intratumoral dose distribution in hepatocellular carcinoma (HCC) patients treated with trans-arterial radioembolization (TARE) using glass microspheres. This study aimed to evaluate the predictive value of dose metrics for treatment response and local progression-free survival (L-PFS).
methodsNinety patients with HCC who underwent TARE between November 2015 and December 2019 were retrospectively analyzed. Post-treatment
resultsAmong 90 patients, 57 (63.3%) achieved CR. PET average dose, D70, V-V
conclusionVoxel-based dosimetry using multiple VSV kernels enables quantitative assessment of intratumoral dose distribution in HCC patients treated with TARE. Among voxel-level parameters, D70, V-V
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