Observational studyInternational ophthalmology2025
The prevalence of epiretinal membrane in pseudoexfoliation and primary open-angle glaucoma and its association with choroidal thickness.
Observational study in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aim to assess epiretinal membrane (ERM) prevalence in pseudoexfoliation glaucoma (PXG) and primary open-angle glaucoma (POAG) eyes and examine its correlation with choroidal thickness (CT) in these individuals.
methodsIn this retrospective, observational study, we examined 165 eyes of 94 PXG patients, 157 eyes of 82 POAG patients, and 150 eyes of 75 healthy individuals. We conducted a comprehensive ophthalmological assessment, including measurements of retinal nerve fiber layer (RNFL) thickness, central macular thickness (CMT), and macular CT using swept-source optical coherence tomography. We also evaluated and categorized posterior vitreous detachment (PVD) presence. ERM staging was performed for eyes with ERM. Lastly, we analyzed the association between ERM presence and CT across all groups.
resultsBCVA and mean RNFL were lower in PXG and POAG groups compared to controls (both p < 0.001). Mean CMT was significantly thinner in PXG versus controls (p < 0.001) and POAG (p = 0.002). ERM prevalence was higher in POAG versus controls and highest in PXG versus both groups. PVD was least in controls, more in POAG, and most in PXG. In PXG with ERM, temporal and nasal CT were higher (p = 0.022, p = 0.016). In the POAG subgroup, eyes receiving prostaglandin analogue therapy had significantly greater subfoveal CT (SFCT) compared with those not undergoing this treatment (p = 0.032).
conclusionAccording to our study, CMT is thinner in PXG eyes. ERM and PVD frequencies increase in POAG and PXG, with higher prevalence in PXG. PXG eyes with ERM exhibit increased nasal and temporal choroidal thickness, and in POAG eyes receiving prostaglandin analogue therapy, SFCT is higher compared to those not receiving this treatment.
Indexed as
Identifiers
41405649What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.