Evidence map›Paper›PMID 41405627›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Changes of head circumference and ventricular width in infant hydrocephalus managed with adjustable shunt valves and gravitational assistance-a comparative bi-center study.

Isabel Fernandes Arroteia, Hans Christoph Bock, Andreas Schaumann, Valentina Pennacchietti, Ahmed El-Garci, Gesa Cohrs, Matthias Schulz, Friederike Knerlich-Lukoschus, Ulrich-Wilhelm Thomale

Abstract readMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isabel Fernandes ArroteiaPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. Isabel.fernandes@charite.de.ORCID 0000-0002-5424-1198
Hans Christoph BockNeurosurgical Department, Göttingen University Hospital, Göttingen, Germany.
Andreas SchaumannPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Valentina PennacchiettiPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Ahmed El-GarciPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Gesa CohrsPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Matthias SchulzPediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Friederike Knerlich-LukoschusNeurosurgical Department, Göttingen University Hospital, Göttingen, Germany.
Ulrich-Wilhelm ThomalePediatric Neurosurgery, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCerebrospinal fluid (CSF) drainage via a ventriculoperitoneal shunt remains to be the most common treatment for infantile hydrocephalus. Since head growth is particularly dynamic and susceptible to intracranial pressure changes during the first months of life, shunting can have a considerable impact. This study aimed to examine changes in head circumference and ventricular width and evaluate their interdependence in children who underwent shunting during infancy with either of two different adjustable valve regimens.

methodsWe conducted a retrospective analysis on synchronized patient databases at two tertiary pediatric neurosurgical centers. One center implanted a differential pressure (DP) adjustable valve with a fixed gravitational unit (aDP

resultsA total of 155 infants (n = 78 in aDP

conclusionsThe present study demonstrates a strong relation between changes in median FOHR and head circumference at the end of follow-up in shunted hydrocephalic infants. In addition, we identified a direct influence of initial valve setting on changes of ventricular width and head circumference at follow-up, underlining the importance of valve resistance for regulating CSF diversion and its anatomical consequences. Further investigations are needed to assess the influence of these parameters on long-term neurodevelopment and functional outcome.

Indexed as

Cerebral VentriclesHeadHydrocephalusVentriculoperitoneal ShuntCephalometryFemaleFollow-Up StudiesGravitationHumansInfantInfant, NewbornMaleRetrospective StudiesDifferential pressure adjustable valveGravitational adjustable valveInfantile hydrocephalusVentriculoperitoneal shunt

Identifiers

PMID41405627
PMCPMC12711991

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.