Evidence map›Paper›PMID 41405425›Full record

ArticleFEMS yeast research2026

Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats.

Justin C Fay, James H Miller, Sofia Dashko, Katie E Hyma, Ping Liu, Helena Volk, Haley Cohen, Nabil F Rahman, Keyang Tang, Emery R Longan and 3 more

Abstract read
In one paragraph

Article in FEMS yeast research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Justin C FayDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.ORCID 0000-0003-1893-877X
James H MillerDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Sofia DashkoWine Research Center, University of Nova Gorica, Vipava SI-5271, Slovenia.
Katie E HymaEvolution, Ecology and Population Biology Program, Washington University, St. Louis, MO 63130, United States.
Ping LiuDepartment of Genetics, Washington University, St. Louis, MO 63110, United States.
Helena VolkWine Research Center, University of Nova Gorica, Vipava SI-5271, Slovenia.
Haley CohenDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Nabil F RahmanDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Keyang TangDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Emery R LonganDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Xueying C LiDepartment of Biology, University of Rochester, Rochester, NY 14627, United States.
Lorena ButinarWine Research Center, University of Nova Gorica, Vipava SI-5271, Slovenia.
Jure PiškurWine Research Center, University of Nova Gorica, Vipava SI-5271, Slovenia.

Funding

Genetic basis and evolution of thermotolerance in the Saccharomyces yeast speciesR01GM080669 · NIGMS · WASHINGTON UNIVERSITY · PI FAY, JUSTIN C · 2007 to 2025
$5.3M
Genetic constraints on adaptive evolutionR35GM156247 · NIGMS · UNIVERSITY OF ROCHESTER · PI Justin C Fay · 2025 to 2026
$617k
European Regional Development Fund 3330-13-500031NIGMS NIH HHS R01 GM080669NIGMS NIH HHS R35 GM156247NIH HHS GM080669Slovenian Research Agency BI-US/13-14-028Slovenian Research Agency J4-4300
6 · The paper itself

Abstract

Humans have generated ecological and environmental disturbances, such as vineyards, across the globe. Disturbed environments create widespread and repeated selective pressures that can drive colonization and local adaptation in microbial species. We investigated the distribution of fermentative yeast species in vineyards compared to nearby arboreal habitats and measured their resistance to two commonly used vineyard antimicrobials, copper and sulfite. We analyzed 4 101 strains, representing 70 species, collected from grapevine- and oak-associated substrates at 17 vineyard and 20 non-vineyard sites in the USA and Slovenia. Species frequency varied with geography and substrate, but the majority of species commonly present in vineyards were also found in non-vineyard arboreal environments, representing a potential source for vineyard colonization and exploitation of sugar from grapes. Species varied in both copper and sulfite resistance, but only Saccharomyces cerevisiae showed elevated resistance in vineyard compared to non-vineyard samples. Our results indicate that S. cerevisiae has uniquely taken advantage of vineyard environments through adaptations that appear either unnecessary or inaccessible to other yeast species present in vineyards.

Indexed as

CopperDrug Resistance, FungalEcosystemSulfitesVitisYeastsSloveniaUnited StatesCopperSulfitesadaptationcolonizationcopperforestsulfitevineyard

Identifiers

PMID41405425
PMCPMC12767201

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.