Evidence map›Paper›PMID 41405354›Full record

ArticleJournal of natural products2026

Alanine Mutagenesis Identifies Specific Amino Acids of Nemertide Alpha-1 Activity and Its Binding to Target Receptors.

Quentin Laborde, Steve Peigneur, Erik Jacobsson, Ulf Göransson, Jan Tytgat, Håkan S Andersson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Quentin LabordePharmacognosy, Department of Pharmaceutical Biosciences, Biomedical Center, Uppsala University, Box 574, SE-751 23, Uppsala, Sweden.
Steve PeigneurToxicology & Pharmacology, University of Leuven (KU Leuven), O&N 2, PO Box 922, Herestraat 49, 3000, Leuven, Belgium.
Erik JacobssonPharmacognosy, Department of Pharmaceutical Biosciences, Biomedical Center, Uppsala University, Box 574, SE-751 23, Uppsala, Sweden.
Ulf GöranssonPharmacognosy, Department of Pharmaceutical Biosciences, Biomedical Center, Uppsala University, Box 574, SE-751 23, Uppsala, Sweden.
Jan TytgatToxicology & Pharmacology, University of Leuven (KU Leuven), O&N 2, PO Box 922, Herestraat 49, 3000, Leuven, Belgium.
Håkan S AnderssonPharmacognosy, Department of Pharmaceutical Biosciences, Biomedical Center, Uppsala University, Box 574, SE-751 23, Uppsala, Sweden.ORCID 0000-0003-1241-8888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently discovered and characterized a novel family of peptide toxins, the alpha-nemertides, from the marine ribbon worm

Indexed as

AlaninePeptidesAnimalsMolecular StructureMutagenesisStructure-Activity RelationshipVoltage-Gated Sodium ChannelsAlaninePeptidesVoltage-Gated Sodium Channels

Identifiers

PMID41405354
PMCPMC12836348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.