Evidence map›Paper›PMID 41405221›Full record

ArticleClinical transplantation2025

Vascular Complications Following Kidney Transplantation From Uncontrolled Donation After Circulatory Death: A Prospective Study.

Alberto Costa Silva, Teresa Pina-Vaz, Ana Pinho, Ana Cerqueira, Inês Ferreira, Manuela Bustorff, Susana Sampaio, Margarida Rios, Roberto Roncon Albuquerque, Manuel Pestana and 3 more

Abstract read
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In one paragraph

Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alberto Costa SilvaUrology Department, University Hospital Center of São João, Porto, Portugal.ORCID https://orcid.org/0000-0001-6753-7206
Teresa Pina-VazUrology Department, University Hospital Center of São João, Porto, Portugal.
Ana PinhoNephrology Department, University Hospital Center of São João, Porto, Portugal.
Ana CerqueiraNephrology Department, University Hospital Center of São João, Porto, Portugal.
Inês FerreiraNephrology Department, University Hospital Center of São João, Porto, Portugal.
Manuela BustorffNephrology Department, University Hospital Center of São João, Porto, Portugal.
Susana SampaioFaculty of Medicine, University of Porto, Porto, Portugal.
Margarida RiosFaculty of Medicine, University of Porto, Porto, Portugal.
Roberto Roncon AlbuquerqueFaculty of Medicine, University of Porto, Porto, Portugal.
Manuel PestanaFaculty of Medicine, University of Porto, Porto, Portugal.
Carlos Martins-SilvaUrology Department, University Hospital Center of São João, Porto, Portugal.
Tiago Antunes-LopesUrology Department, University Hospital Center of São João, Porto, Portugal.
João Alturas SilvaUrology Department, University Hospital Center of São João, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVascular complications in kidney transplantation are a major concern. While kidneys from uncontrolled donation after circulatory death (uDCD) offer a viable organ source, the incidence of vascular complications in these cases remains poorly studied. This study aims to compare the vascular complications between transplants from uDCD and donation after brain death (DBD).

methodsBetween January 2016 and November 2023, we performed a prospective analysis concerning vascular complications (arterial and venous) based on kidney transplants from uDCD and DBD with standard criteria (SCD) or expanded criteria (ECD).

resultsAmong the 523 kidney transplants, 142 were from uDCD and, of those, 7.0% had vascular complications comprising arterial (2.8%) and venous (4.2%) complications. The rates of vascular complications showed no significant difference between kidney transplants from uDCD and SCD (7.0% vs. 3.1%, p = 0.120) and between uDCD and ECD (7.0% vs. 8.5%, p = 0.766). Donor age over 50 years was associated with vascular complications in uDCD (p = 0.016). The incidence of delayed graft function was significantly higher in the uDCD group compared with SCD and ECD (69.7% vs. 37.6% and 43.9%, respectively; p < 0.001).

conclusionVascular complication rates in uDCD transplantation were comparable to those in SCD and ECD transplants. Donor age appears to be a contributing factor to vascular complications in the uDCD setting. While these findings suggest similar outcomes, the small number of events highlights the need for larger studies.

Indexed as

Delayed Graft FunctionGraft RejectionKidney TransplantationPostoperative ComplicationsTissue and Organ ProcurementTissue DonorsVascular DiseasesAdultBrain DeathFemaleFollow-Up StudiesGlomerular Filtration RateGraft SurvivalHumansIncidenceKidney Function Testsextracorporeal membrane oxygenationkidney transplantationorgan donationperoperative complicationthrombosis

Identifiers

PMID41405221
PMCPMC12710453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.