Evidence map›Paper›PMID 41405192›Full record

ArticleCancer medicine2025

Contemporary Area-Level Mortgage Loan Denial Risk and Health-Related Quality of Life Among Cancer Survivors.

Jordyn A Brown, Taylor D Ellington, Leah Moubadder, Maya Bliss, Anjali D Kumar, Chantel L Martin, Laura Farnan, Adrian Gerstel, Lauren E McCullough, Hazel B Nichols

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jordyn A BrownDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-3802-0667
Taylor D EllingtonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Leah MoubadderDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Maya BlissDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Anjali D KumarDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Chantel L MartinDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Laura FarnanLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Adrian GerstelLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Lauren E McCulloughDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Hazel B NicholsDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-0972-1560

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in GeorgiaR01CA259192 · NCI · EMORY UNIVERSITY · PI MCCULLOUGH, LAUREN E · 2021 to 2025
$2.9M
NCI NIH HHS P30 CA016086NCI NIH HHS R01 CA259192NCI NIH HHS R01CA259192NCI NIH HHS T32 CA057726NCI NIH HHS T32CA057726NCI NIH HHS T32 CA116339NCI NIH HHS T32CA116339
6 · The paper itself

Abstract

backgroundHistorical and contemporary mortgage lending practices have been associated with worse cancer outcomes. We estimated the association between mortgage loan denial risk and health-related quality of life (HRQoL) among survivors at a large tertiary medical center in North Carolina (NC).

methodsMortgage denial risk, calculated using Home Mortgage Disclosure Act data (2010-2014), was linked by census tract to UNC Cancer Survivorship Cohort survivors who resided within NC metropolitan statistical areas (MSAs). HRQoL was measured using the validated Functional Assessment of Cancer Therapy-General (FACT-G). Differences in well-being across seven MSAs were assessed using Pearson chi-square tests and modified Poisson regression models adjusted for demographic and socioeconomic characteristics.

resultsOver 40% of survivors reported low overall well-being, while more than one-third of survivors reported low physical, social, emotional, or functional well-being. FACT-G scores were 6.2 (95% CI: 1.5, 10.9) points lower among Greensboro survivors; 4.1 (95% CI: 0.1, 8.1) points lower among Fayetteville MSA survivors; and 9.6 (95% CI: 2.5, 16.8) points lower among Charlotte survivors at a higher risk for mortgage loan denial compared to those at lower risk. Racial differences in FACT-G scores were only observed among Greensboro and Charlotte MSA survivors, whereas sex differences were limited to Charlotte survivors.

conclusionsMortgage loan denial was associated with worse overall HRQoL in Greensboro, Fayetteville, and Charlotte, but not in other NC MSAs. Further investigation into the role of place in other NC MSAs is needed to identify opportunities to support survivors across the cancer control continuum.

Indexed as

Cancer SurvivorsNeoplasmsQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedNorth Carolinacancer survivorshipquality of liferesidential segregationsocial determinants of healthstructural inequitiesstructural racism

Identifiers

PMID41405192
PMCPMC12710087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.