Evidence map›Paper›PMID 41405048›Full record

ArticleThe journal of extra-corporeal technology2025

Delta-P as an early indicator of oxygenator failure: the case for standardized manufacturer reference values.

Salman Pervaiz Butt, Salman Abdulaziz, Ashwaq Mahdaly, Nabeel Razzaq, Drisya Paul, Umer Darr, Gopal Bhatnagar

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of extra-corporeal technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Salman Pervaiz ButtPerfusion Services, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO Box 112412, Abu Dhabi, United Arab Emirates.
Salman AbdulazizCritical Care Services Administration, As Sulimaniyah, Makkah rd, Riyadh 12231, Saudi Arabia.
Ashwaq MahdalyDepartment of Critical Care, As Sulimaniyah, Makkah rd, Riyadh 12231, Saudi Arabia.
Nabeel RazzaqHeart Vascular and Thoracic Institute, Cleveland Clinic, PO Box 112412, Abu Dhabi, United Arab Emirates.
Drisya PaulHeart Vascular and Thoracic Institute, Cleveland Clinic, PO Box 112412, Abu Dhabi, United Arab Emirates.
Umer DarrHeart Vascular and Thoracic Institute, Cleveland Clinic, PO Box 112412, Abu Dhabi, United Arab Emirates.
Gopal BhatnagarHeart Vascular and Thoracic Institute, Cleveland Clinic, PO Box 112412, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of extracorporeal membrane oxygenation (ECMO) has led to an increasing reliance on objective parameters to detect complications early and enhance patient safety. One such parameter is the transmembrane pressure gradient, more commonly referred to as delta P (ΔP), the difference between the inlet and outlet pressures of the oxygenator. This measure has increasingly been recognized as a critical early indicator of thrombus formation within the oxygenator during ECMO support. However, its interpretation remains complex and context-dependent, particularly because delta P values are significantly influenced by the design features of different ECMO circuits, including pump head geometry and oxygenator configuration.

Indexed as

Blood CoagulationEquipment Failure AnalysisExtracorporeal Membrane OxygenationEquipment DesignHumansPatient SafetyPressureReference ValuesDelta-P monitoringECMO circuit safetyOxygenator thrombosis

Identifiers

PMID41405048
PMCPMC12710228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.