Evidence map›Paper›PMID 41404872›Full record

ArticleMicrobiology spectrum2026

Biogeographical and phylogenetic constraints on horizontal gene transfer and genome evolution in

Janani Hariharan, Cheryl P Andam, Daniel H Buckley

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Oxytetracycline ProducerInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Janani HariharanSchool of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-5535-4119
Cheryl P AndamSchool of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-4428-0924
Daniel H BuckleySchool of Integrative Plant Science, Cornell University, Ithaca, New York, USA.

Funding

National Science Foundation 1456821National Science Foundation 2055120
6 · The paper itself

Abstract

The role of horizontal gene transfer (HGT) in shaping bacterial genomes is well recognized, but constraints on gene exchange and the degree to which these constraints shape genome evolution remain poorly described. In this study, we sought to determine whether geographic and phylogenetic distance constrains HGT within and between bacterial species. To address this question, we isolated strains ( IMPORTANCE: Horizontal gene transfer (HGT) is a vital ecological and evolutionary force in microbiology, but we still lack a precise understanding of how precisely HGT acts on the gene pool of a species or genus. While HGT can complicate phylogenetic analyses and assumptions of homology, its role in adaptation and acquiring secondary metabolites should not be overlooked. Microbial ecologists agree that the pangenome is a shifting collection of genes that can be influenced by both vertical inheritance and ecological factors. This study examines how the

Indexed as

Evolution, MolecularGene Transfer, HorizontalGenome, BacterialPhylogenyStreptomycesMultigene FamilySecondary Metabolismactinophagebiogeographycomparative genomicshorizontal gene transferpangenomesecondary metaboliteStreptomyces

Identifiers

PMID41404872
PMCPMC12889140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.