Evidence map›Paper›PMID 41404618›Full record

ArticlebioRxiv : the preprint server for biology2025

Linear Z-line-like alignment of capping protein in obliquely striated muscle of the nematode

Shoichiro Ono, Emily Nickoloff-Bybel, Kennosuke Kurimaru, Kanako Ono

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Shoichiro OnoDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.ORCID 0000-0002-4763-0398
Emily Nickoloff-BybelDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Kennosuke KurimaruDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Kanako OnoDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Actin regulation by cyclase-associated proteinR01GM144563 · NIGMS · EMORY UNIVERSITY · PI Shoichiro Ono · 2024 to 2026
$939k
NIGMS NIH HHS R01 GM144563NIH HHS P40 OD010440
6 · The paper itself

Abstract

Many invertebrates have obliquely striated muscles, in which neighboring thin and thick filaments are staggered and aligned in an oblique manner. This type of muscle allows force production over a wide range of lengths and is beneficial for soft-bodied animals. Unlike cross-striated muscles of vertebrates, most of obliquely striated muscles lack distinct Z-lines and, instead, have dense bodies. Because the dense bodies are located in the middle of the I-bands and contain α-actinin, the dogma is that dense bodies are equivalent to the Z-lines anchoring the actin barbed ends. However, we present evidence that the barbed ends of sarcomeric actin filaments in the nematode

Identifiers

PMID41404618
PMCPMC12703992

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.