Evidence map›Paper›PMID 41404465›Full record

ArticleFrontiers in neurology2025

May vestibular rehabilitation reduce apnea-hypopnea index in patients with obstructive sleep apnea? A pilot study.

Annalisa Pace, Giannicola Iannella, Saverio Nicoletti, Paola Di Mauro, Francesca Mattioli, Salvatore Cocuzza, Antonino Maniaci, Danilo Alunni Fegatelli, Annarita Vestri, Giuseppe Magliulo

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In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Annalisa PaceDepartment of Sensory Organs, Sapienza University of Rome, Rome, Italy.
Giannicola IannellaDepartment of Sensory Organs, Sapienza University of Rome, Rome, Italy.
Saverio NicolettiDepartment of Sensory Organs, Sapienza University of Rome, Rome, Italy.
Paola Di MauroDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" University of Catania, Catania, Italy.
Francesca MattioliDepartment of Sensory Organs, Sapienza University of Rome, Rome, Italy.
Salvatore CocuzzaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" University of Catania, Catania, Italy.
Antonino ManiaciDepartment of Medicine and Surgery, University of Enna Kore, Enna, Italy.
Danilo Alunni FegatelliDepartment of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy.
Annarita VestriDepartment of Public Health and Infection Diseases, Sapienza University of Rome, Rome, Italy.
Giuseppe MagliuloDepartment of Sensory Organs, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The vestibular system is essential for maintaining the perception of head orientation and acceleration in all directions. The Functional Head Impulse Test (fHIT) is a novel tool for assessing the vestibulo-ocular reflex (VOR) and forms the basis for a recently developed vestibular rehabilitation system. This pilot study aimed to determine whether vestibular rehabilitation alone could objectively improve clinical parameters in patients with obstructive sleep apnea (OSA). Methods: Twenty male patients diagnosed with OSA underwent baseline polysomnography (PSG) and fHIT assessment. Participants then completed a 10-day vestibular rehabilitation program using the reHAB system, after which PSG and fHIT were repeated. Results: Initial fHIT analysis indicated impaired vestibular function in 30% of patients. The Wilcoxon signed-rank test demonstrated a statistically significant reduction in the apneahypopnea index (AHI) following rehabilitation ( Discussion: These preliminary findings suggest a functional connection between vestibular inputs and sleep-wake pathways, possibly mediated by parabrachial circuits and orexinergic modulation.

Indexed as

apnea-hypopnea indexFunctional Head Impulse Testobstructive sleep apneapolysomnographyvestibular rehabilitationvestibular system

Identifiers

PMID41404465
PMCPMC12703877

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.