Evidence map›Paper›PMID 41404446›Full record

ArticleCureus2025

Silent Separation: Uterine Dehiscence After Second-Trimester Termination in Monochorionic Diamniotic Twins.

Ayisha Ejaz Bhutta, Karen E Austin-Smith, Wael Abdulkareem, Nimatallah Omoteso

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayisha Ejaz BhuttaDepartment of Obstetrics and Gynaecology, Kettering General Hospital, Kettering, GBR.
Karen E Austin-SmithDepartment of Obstetrics and Gynaecology, Kettering General Hospital, Kettering, GBR.
Wael AbdulkareemDepartment of Obstetrics and Gynaecology, Kettering General Hospital, Kettering, GBR.
Nimatallah OmotesoDepartment of Obstetrics and Gynaecology, Kettering General Hospital, Kettering, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine rupture is a rare but life-threatening complication, most commonly associated with labor in women with a prior caesarean scar. Its occurrence in the second trimester, particularly in primigravid women with an unscarred uterus, is exceptionally uncommon. Here, we present a 29-year-old primigravida with a monochorionic-diamniotic (MCDA) twin pregnancy complicated by absent end-diastolic flow in one twin and subsequent intrauterine fetal demise at 21+5 weeks. Induction of labor with misoprostol resulted in delivery at 21+6 weeks. The early postpartum course was complicated by pyrexia, retained tissue, and recurrent heavy bleeding requiring ultrasound-guided surgical evacuation (SEVAC), uterine balloon tamponade, and major obstetric hemorrhage. Thirty-two days post-delivery, the patient collapsed with secondary postpartum hemorrhage. MRI later demonstrated a complete absence of the anterior uterine wall, consistent with rupture/dehiscence. Laparotomy confirmed a large anterior wall defect, which was successfully repaired, preserving fertility. This case gives us insight that second-trimester uterine rupture, though rare, is a potentially devastating condition. Clinicians should remain vigilant regardless of parity or uterine history. "Silent rupture" emphasizes the role of imaging in ambiguous cases. Conservative measures for postpartum hemorrhage must be used judiciously, and prompt surgical management optimizes outcomes and preserves fertility. Larger studies are needed to refine risk stratification and monitoring strategies.

Indexed as

bakri ballooncase reportmisoprostolsecond-trimester inductiontwin pregnancyuterine rupture

Identifiers

PMID41404446
PMCPMC12703635

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.