Evidence map›Paper›PMID 41404440›Full record

ArticleProceedings. IEEE International Symposium on Biomedical Imaging2024

ENHANCING GENERALIZABILITY IN BRAIN TUMOR SEGMENTATION: MODEL ENSEMBLE WITH ADAPTIVE POST-PROCESSING.

Zhifan Jiang, Daniel Capellán-Martín, Abhijeet Parida, Xinyang Liu, María J Ledesma-Carbayo, Syed Muhammad Anwar, Marius George Linguraru

Abstract read
In one paragraph

Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Adaptable Segmentation Pipeline for Diverse Brain Tumors with Radiomic-guided Subtyping and Lesion-Wise Model Ensemble.Segmentation, classification, and synthesis for brain tumors and traumatic brain injuries : MICCAI 2025 Challenges: BraTS-Lighthouse 2025 and AIMS-TBI 2025, held in conjunction with MICCAI 2025, Daejeon, South Korea, September 23, 2025,... · 2026
    Article
  2. Improving Pre-trained Adult Glioma Segmentation Models using only Post-processing Techniques.Segmentation, classification, and synthesis for brain tumors and traumatic brain injuries : MICCAI 2025 Challenges: BraTS-Lighthouse 2025 and AIMS-TBI 2025, held in conjunction with MICCAI 2025, Daejeon, South Korea, September 23, 2025,... · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhifan JiangSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Daniel Capellán-MartínSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Abhijeet ParidaSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Xinyang LiuSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
María J Ledesma-CarbayoBiomedical Image Technologies, ETSI Telecomunicación, Universidad Politécnica de Madrid & CIBER-BBN, Madrid, Spain.
Syed Muhammad AnwarSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Marius George LinguraruSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.

Funding

Quantitative MRI for Pediatric Optic Pathway Glioma Treatment ResponseUG3CA236536 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI AVERY, ROBERT ANDREW, LINGURARU, MARIUS GEORGE · 2020 to 2021
$923k
NCI NIH HHS UG3 CA236536
6 · The paper itself

Abstract

Segmentation of brain tumors in multi-parametric magnetic resonance imaging facilitates quantitative analysis crucial for clinical trials and personalized patient care. This significantly influences clinical decision-making, encompassing diagnosis and prognosis and enhancing patient outcomes. The brain tumor segmentation (BraTS) challenge, in its 2023 edition, extended to a cluster of competitions incorporating multiple tumor types. Now, in conjunction with IEEE ISBI 2024, BraTS organizes its Generalizability Across Tumors (BraTS-GoAT) challenge. In this paper, we introduce a deep-learning-based ensemble strategy involving three state-of-the-art segmentation models. Furthermore, we also introduce a novel adaptive post-processing method, based on a cross-validated tumor-specific threshold search, designed to output enhanced accurate segmentations, ensuring generalizability across various tumor types. The evaluation of our proposed method on validation cases resulted in lesion-wise Dice scores of 0.842, 0.854, 0.872 and lesion-wise 95th-percentile Hausdorff Distance scores of 29.46, 24.67, 25.22 for the enhancing tumor, tumor core, and whole tumor, respectively.

Indexed as

Brain tumor segmentationDeep learningGeneralizabilityMRIUnsupervised learning

Identifiers

PMID41404440
PMCPMC12704145

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.