Evidence map›Paper›PMID 41404363›Full record

ArticlePain reports2026

Sex differences in pain in 2 large and diverse US databases.

Soyoung Han, Ariadne Letra, Anna Alessandri-Bonetti, Davis Thomas, Flavia P Kapos, Linda Sangalli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pain reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Soyoung HanBiomedical Science, Graduate Studies, Midwestern University, Downers Grove, IL, USA.
Ariadne LetraDepartment of Oral and Craniofacial Sciences, Center for Craniofacial and Dental Genetics, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.
Anna Alessandri-BonettiInstitute of Dental Clinic, A. Gemelli University Policlinic IRCCS, Catholic University of Sacred Heart, Rome, Italy.
Davis ThomasDepartment of Diagnostic Sciences, Center for Temporomandibular Disorders and Orofacial Pain, Rutgers School of Dental Medicine, Newark, NJ, USA.
Flavia P KaposDepartment of Orthopaedic Surgery and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.ORCID https://orcid.org/0000-0002-6224-273X
Linda SangalliCollege of Dental Medicine-Illinois, Midwestern University, Downers Grove, IL, USA.

Funding

Mentoring in Musculoskeletal Pain PhenotypesK24AR079594 · NIAMS · DUKE UNIVERSITY · PI Adam Goode · 2022 to 2026
$927k
NIAMS NIH HHS K24 AR079594
6 · The paper itself

Abstract

Introduction: Sex differences have been recognized as significant influences on disease suceptibility and progression. Objectives: This study aimed to assess sex differences in pain prevalence using 2 large and diverse US data sources, Methods: Pain concepts, labels used to describe type, chronicity, and body locations in electronic health records, were identified from 254,639 individuals in Results: The search yielded 195 pain concepts available in both Conclusion: Higher pain prevalence among females in the United States was observed for most pain concepts in 2 large and diverse databases. These results underscore the importance of pain research, prevention, and management approaches stratified by sex.

Indexed as

All of UsEpic cosmosEpidemiologyPainSex differences

Identifiers

PMID41404363
PMCPMC12705055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.