ArticlePain reports2026
Unspecified pain, chronic pain, and high-impact chronic pain in Lesotho: a population-based cross-sectional study.
Article in Pain reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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13 authors.
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Abstract
Objectives: Pain is understudied in Africa, and there are no data on high-impact chronic pain from this region. In this study, we assessed the prevalence of unspecified pain, chronic pain, and high-impact chronic pain, and their determinants in Lesotho, Southern Africa. Method: We conducted a household-based, cross-sectional survey among adults aged 18 years or older in 120 randomly sampled villages across Butha-Buthe and Mokhotlong districts in Lesotho. Results: Among the 6039 adults included, the median age was 39 years (interquartile range: 27-58), and 3153 of 6039 participants (52.2%) were female. Overall, 1194 participants (19.8%) had unspecified pain (95% confidence interval [CI]: 18.8-20.8), 909 (15.1%) had chronic pain (95% CI: 14.2-16.0), and 428 (7.1%) had high-impact chronic pain (95% CI: 6.5-7.8) corresponding to 47.1% among the participants with chronic pain. Higher age groups were associated with increasing odds of unspecified pain, chronic pain, and high-impact chronic pain. Male participants were less likely to have unspecified pain (adjusted odds ratio [aOR], 0.65; 95% CI: 0.55-0.76; Conclusion: The prevalence of chronic pain and high-impact chronic pain was elevated in our study population. Associations with further noncommunicable chronic conditions, such as arterial hypertension and diabetes mellitus, support the need for health systems to provide integrated chronic care which includes pain management.
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