ArticleCureus2025
Pre-ductal and Post-ductal Oxygen Saturation Trends in Neonates: A Cross-Sectional Observational Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The transition from fetal to neonatal life involves significant physiological changes, particularly in arterial oxygen saturation (SpO₂), which can be visually observed as skin color changes. However, visual assessment alone is prone to variability. Pulse oximetry offers a reliable, non-invasive method to monitor SpO₂ levels, providing critical information on newborn oxygenation and aiding in the early detection of critical congenital heart diseases (CCHD). Methods This observational cross-sectional study was conducted at a tertiary care center over 18 months, involving 250 newborns. Pre-ductal and post-ductal SpO₂ were measured using pulse oximeters at 2, 3, 4, 5, 10, and 15 minutes or until levels surpassed 90%. Data analysis was performed using Student's t-test and the Mann-Whitney U test, with a significance threshold of p < 0.05. Results The mean time for pre-ductal SpO₂ to reach 90% was 8.68 minutes, while post-ductal SpO₂ took 9.05 minutes. The time for pre-ductal and post-ductal SpO₂ to equalize was 11.57 minutes. Maternal age, gestational age, birth weight, and maternal hemoglobin levels had minimal impact on SpO₂ stabilization. Conclusion This study highlights the critical role of oxygen supplementation in accelerating SpO₂ stabilization and the influence of maternal comorbidities on neonatal oxygenation. Despite minimal impact from other factors, targeted monitoring and intervention are essential, particularly for newborns born to mothers with health conditions. These insights emphasize the need for tailored neonatal care strategies to optimize outcomes during this critical period of adaptation. Targeted oxygen supplementation and maternal comorbidity screening may help optimize neonatal transition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.