ArticleCureus2025
The Red Herring Cast: Interstitial Nephritis in Disguise.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 36-year-old man with a 12-year history of type 2 diabetes mellitus and recently diagnosed hypertension presented with oliguria, edema, and rapidly progressive renal dysfunction. Urinalysis revealed nephritic sediment with significant proteinuria, red blood cells (RBCs), and cellular casts, raising a strong suspicion for rapidly progressive glomerulonephritis. However, renal biopsy showed acute on chronic interstitial nephritis characterized by dense lymphoplasmacytic infiltrates, tubular atrophy, regenerative atypia, and moderate interstitial fibrosis, without crescents or immune deposits. This case highlights the diagnostic challenge of acute interstitial nephritis (AIN) mimicking glomerular disease in diabetic patients. Early biopsy was essential to avoid misclassification and inappropriate immunosuppression. The report underscores the importance of considering interstitial pathology in atypical or rapidly worsening renal failure among diabetics and reinforces the role of kidney biopsy as the gold standard for accurate diagnosis and appropriate management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.