Evidence map›Paper›PMID 41404196›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Regenerative potential of nanoenabled collagen-polylactide scaffolds for osteochondral defect repair in rabbits.

Lena Schröter, Graciosa Quelhas Teixeira, Luisa de Roy, Benjamin Thilo Krüger, Oliver Küppers, Catarina Leite Pereira, Daniela Pereira Vasconcelos, Meriem Lamghari, Bruno Sarmento, Geir Klinkenberg and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lena Schröter *Institute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Graciosa Quelhas Teixeira *Institute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Luisa de RoyInstitute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Benjamin Thilo KrügerInstitute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Oliver KüppersInstitute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Catarina Leite PereiraInstituto de Investigação e Inovação em Saúde (i3S), Instituto Nacional de Engenharia Biomédica (INEB), Universidade do Porto, Porto, Portugal.
Daniela Pereira VasconcelosInstituto de Investigação e Inovação em Saúde (i3S), Instituto Nacional de Engenharia Biomédica (INEB), Universidade do Porto, Porto, Portugal.
Meriem LamghariInstituto de Investigação e Inovação em Saúde (i3S), Instituto Nacional de Engenharia Biomédica (INEB), Universidade do Porto, Porto, Portugal.
Bruno SarmentoInstituto de Investigação e Inovação em Saúde (i3S), Instituto Nacional de Engenharia Biomédica (INEB), Universidade do Porto, Porto, Portugal.
Geir KlinkenbergSINTEF Industry, Department of Biotechnology and Nanomedicine, Trondheim, Norway.
Ruth SchmidSINTEF Industry, Department of Biotechnology and Nanomedicine, Trondheim, Norway.
Raquel GraciaCIDETEC, Basque Research and Technology Alliance (BRTA), Parque Científico y Tecnológico de Gipuzkoa, Donostia-San Sebastián, Spain.
Janire AlkortaCIDETEC, Basque Research and Technology Alliance (BRTA), Parque Científico y Tecnológico de Gipuzkoa, Donostia-San Sebastián, Spain.
Damien DupinCIDETEC, Basque Research and Technology Alliance (BRTA), Parque Científico y Tecnológico de Gipuzkoa, Donostia-San Sebastián, Spain.
Anne-Marie HaaparantaAskel Healthcare Ltd., Tampere, Finland.
Virpi MuhonenAskel Healthcare Ltd., Tampere, Finland.
Andreas Martin SeitzInstitute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.
Anita IgnatiusInstitute of Orthopaedic Research and Biomechanics, Ulm University Medical Center, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current tissue engineering strategies for treating traumatic or degenerative cartilage defects in osteoarthritis (OA) remain insufficient in promoting robust tissue regeneration while simultaneously addressing inflammation, matrix degradation, and post-surgical infections. In this study, we evaluated the

Indexed as

biomaterialscartilage tissue engineeringimmunomodulationinflammationnanoenabled scaffoldsosteoarthritis

Identifiers

PMID41404196
PMCPMC12702961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.