Evidence map›Paper›PMID 41404143›Full record

ArticleFrontiers in plant science2025

Genetic suppressor of

Katherine A Klimpel, Annika Findlay, Sannidhi Menon, Leah Cytron-Walker, Caylynn A Dedow, Lazlo Camou, Michela Cadarso, Meghan F McGuire, Jeff Pietroske, Daniel Idowu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katherine A KlimpelLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Annika FindlayLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Sannidhi MenonLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Leah Cytron-WalkerLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Caylynn A DedowLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Lazlo CamouLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Michela CadarsoLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Meghan F McGuireLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Jeff PietroskeLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Daniel IdowuLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Michael BuscheLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.
Jacob O BrunkardLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI, United States.

Funding

A tRNA synthetase is an amino acid sensor for TOR in plantsR01GM145814 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jacob O Brunkard · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM145814
6 · The paper itself

Abstract

Introduction: A classical forward genetic screen for Arabidopsis mutants with altered morphology identified a pleiotropic mutant, Methods: To discover why this glutamate synthase impacts development, we conducted a forward genetic screen for suppressors of Results: We found that inhibiting brassinosteroid synthesis significantly increases chlorophyll content in Discussion: This discovery highlights how crosstalk among phytohormones (brassinosteroids) and core metabolic processes (amino acid biosynthesis and photorespiration) converge to regulate plant development and physiology.

Indexed as

brassinosteroidgibberellinglutamate synthasephotorespirationplant geneticsplant hormonesplant metabolism

Identifiers

PMID41404143
PMCPMC12702938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.