Evidence map›Paper›PMID 41404032›Full record

ReviewFrontiers in neuroscience2025

From environment to brain: the role of microplastics in neurobehavioral disorders.

Shan Zhang, Jianbing Wu, Mei Wu, Yuan Qin, Nan Zhu, Yijia Shen, Rong Chen, Zhujun Chen

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shan ZhangZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Jianbing WuZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Mei WuZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Yuan QinZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Nan ZhuZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Yijia ShenZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Rong ChenZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.
Zhujun ChenZhangjiagang Center for Disease Control and Prevention, Zhangjiagang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the pervasive presence of microplastics has attracted significant attention from the scientific community, particularly concerning their potential implications for human health. Current literature suggests that microplastics may adversely affect the nervous system, with emerging evidence linking them to neurobehavioral disorders. However, many questions remain regarding the pathways of their environmental exposure, the specific effects on neurobehavior, and the underlying mechanisms of their impact. This review aims to explore the routes through which humans are exposed to microplastics, monitor behavioral changes associated with microplastic exposure, and examine how these particles infiltrate the body and traverse the blood-brain barrier. Several perspectives will be considered in assessing the potential mechanisms by which microplastics may influence neurobehavioral disorders, including oxidative stress, neurotransmitter regulation, and neuroplasticity. The article concludes by summarizing the effects of microplastics on neurobehavioral disorders, such as neurodegeneration and mood disorders, while analyzing the latest research findings. The primary objective of this study is to elucidate the neurotoxic effects of microplastics and their potential biological mechanisms, as well as to provide new insights and recommendations for future research in this domain.

Indexed as

environmental effectsmicroplasticsnanoplasticsneurobehavioral disordersneurotoxicity

Identifiers

PMID41404032
PMCPMC12702878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.