Evidence map›Paper›PMID 41403980›Full record

ArticleClinical case reports2025

Adult-Onset Still's Disease Complicated by Secondary Hemophagocytic Lymphohistiocytosis: A Case Report.

Vasileios Patriarcheas, Vasiliki Gougoula, Michail Makris, Athanasios Penopoulos, Eleftheria Ztriva, Stavroula Bountola, Theodoros Dimitroulas, Christos Savopoulos, Georgia Kaiafa

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Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vasileios PatriarcheasFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.ORCID https://orcid.org/0000-0001-6561-321X
Vasiliki GougoulaFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Michail MakrisFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Athanasios PenopoulosFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Eleftheria ZtrivaFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Stavroula BountolaFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Theodoros Dimitroulas4th Department of Internal Medicine Aristotle University of Thessaloniki, Hippokration General Hospital Thessaloniki Greece.
Christos SavopoulosFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.
Georgia KaiafaFirst Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital Thessaloniki Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult-onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by fever, rash, joint pain, and elevated ferritin levels. Systemic inflammation can trigger an exaggerated immune response, leading to secondary hemophagocytic lymphohistiocytosis (HLH). This case discusses AOSD complicated by HLH in a 29-year-old female, emphasizing prompt recognition and management.

Indexed as

adult‐onset Still's disease (AOSD)macrophage activation syndrome (MAS)secondary hemophagocytic lymphohistiocytosis (HLH)

Identifiers

PMID41403980
PMCPMC12703011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.