ArticleChina CDC weekly2025
Outbreak of Chikungunya Virus with
Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Viral kinetics of the Chikungunya virus ESCA-MAL lineage during the 2025 Guangdong outbreak.Virologica Sinica · 2026Article
- Chikungunya virus: global epidemiology, transmission dynamics, and emerging challenges for public health.Infection · 2026Review
- Article
- The Vector-Proofing Gap in Sponge City Design: Implications for Arboviral Risk Under Climate Adaptation - Guangdong Province, China, 2025.China CDC weekly · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What is already known about this topic?: The circulating strain in the recent Chikungunya fever outbreak in Guangdong Province belongs to the East/Central/South African (ECSA) genotype. However, the specific mutations in the viral genome remained unclear. What is added by this report?: This study conducted whole-genome sequencing of viral sequences from clinical samples. The results confirmed that the epidemic strain belongs to the Middle African Lineage (MAL) within the ECSA genotype, not the Indian Ocean Lineage (IOL). Further analysis of nucleotide mutations revealed several adaptive mutations compared with the S27 genomic sequence (NC_004162), such as E1-A226V, E2-L210Q, and E2-I211T. What are the implications for public health practice?: Based on previous genomic surveillance and pathogen studies, mutations like E1-A226V, E2-L210Q, and E2-I211T were generally considered characteristic of IOL within the ECSA genotype and are known to enhance viral replication and transmission efficiency in
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