Evidence map›Paper›PMID 41403922›Full record

ArticleChina CDC weekly2025

The First Imported Case of Chikungunya Virus Infection - Anhui Province, China, 2025.

Liangzi Guo, Jun He, Sai Hou, Ziqing Yuan, Junling Yu, Zhaoqian Meng, Guoxia Guo, Xialian Gao, Huaibiao Li, Lei Gong and 8 more

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Liangzi Guo *Fuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Jun He *Department of Microbiology Laboratory, Anhui Provincial Academy of Preventive Medicine, Hefei City, Anhui Province, China.
Sai HouAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Ziqing YuanFuyang Second People's Hospital, Fuyang City, Anhui Province, China.
Junling YuAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Zhaoqian MengFuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Guoxia GuoFuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Xialian GaoFuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Huaibiao LiFuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Lei GongAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Yinxu HouAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Jialin ZhangAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Xiuzhi ChenAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Yujie FengAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Xiaofeng LyuAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.
Tuantuan LiFuyang Second People's Hospital, Fuyang City, Anhui Province, China.
Ge BuFuyang Center for Disease Control and Prevention, Fuyang City, Anhui Province, China.
Jiabing WuAnhui Provincial Center for Disease Control and Prevention, Hefei City, Anhui Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Since China's first imported Chikungunya fever (CHIKF) case in 2008, 16 provinces have reported cases, primarily imported from endemic areas in Southeast Asia, South Asia, and Africa. Most of China, including Anhui Province, is non-endemic; Anhui had no cases prior to August 2025. What is added by this report?: This report documents the first laboratory-confirmed imported case of Chikungunya virus (CHIKV) infection in Anhui Province and presents the complete viral genome sequence. Comprehensive clinical documentation characterizes the patient's symptoms in detail, including fever, arthralgia, and cutaneous manifestations, thereby addressing a critical gap in the regional clinical profile of CHIKV infection. Comparative analysis of real-time fluorescent quantitative polymerase chain reaction (qPCR) and Enzyme-Linked Immunosorbent Assay (ELISA) results demonstrated that nucleic acid testing provides superior sensitivity during the acute phase of infection. What are the implications for public health practice?: This case underscores China's escalating CHIKF risk. Key implications are: 1) Establishing a cross-regional surveillance network is vital for enhanced case and vector detection sensitivity; 2) In non-endemic areas, strengthening public health education on CHIKV risks is essential for imported disease control. Effectively reducing the burden of vector-borne diseases requires strengthened international cooperation, multi-sectoral collaboration, and innovative technologies.

Indexed as

Chikungunya feverChikungunya virus

Identifiers

PMID41403922
PMCPMC12702662

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.