Evidence map›Paper›PMID 41403813›Full record

ArticleMaedica2025

Redefining Minimally Invasive Head and Neck Surgery without Robotics: the First Romanian TOUSS Experience.

Simona-Andreea Rujan, Serban Vifor Gabriel Bertesteanu, Raluca Grigore, Bogdan Popescu, Mihnea Condeescu-Cojocarita, Alexandru Nicolaescu, Gloria Simona Bertesteanu, Teodora Elena Schipor-Diaconu, Mihai Dumitru Tudosie, Irina Doinita Popescu and 1 more

Abstract read
In one paragraph

Article in Maedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simona-Andreea RujanDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Serban Vifor Gabriel BertesteanuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Raluca GrigoreDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Bogdan PopescuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mihnea Condeescu-CojocaritaDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alexandru NicolaescuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Gloria Simona BertesteanuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Teodora Elena Schipor-DiaconuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mihai Dumitru TudosieDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Irina Doinita PopescuDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Bianca Petra TaherDepartment 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transoral ultrasonic surgery (TOUSS) has emerged as a minimally invasive technique for the treatment of head and neck malignancies, offering oncologic outcomes comparable to robotic-assisted approaches, but with lower costs and wider accessibility. Objective: This study aims to evaluate the clinical and functional outcomes of TOUSS in a single-institution cohort, including the first documented cases of total transoral laryngectomy performed via TOUSS in Romania. Methods: A retrospective observational analysis was conducted on 39 patients treated at Colțea Clinical Hospital between 2018 and 2024. Eligible patients had T1-T3 squamous cell carcinomas of the oropharynx, oral cavity, supraglottis, or larynx, with appropriate transoral exposure. Data on demographics, tumor characteristics, perioperative outcomes and three-year follow-up were collected. Results: The majority of tumors involved the oropharynx (n=21), followed by the lateral or base of the tongue (n=14), with two cases requiring total laryngectomy. Tracheostomy was avoided in all patients. Nasogastric tube removal occurred by day 10, and the average hospital stay was seven days. At three years, 79.5% of patients remained disease-free, with 10.3% recurrence and 10.3% lost to follow-up. Postoperative complications were minimal and surgically controlled. Conclusion: Transoral ultrasonic surgery is a safe and effective alternative to robotic surgery, achieving favorable oncologic and functional outcomes. Its feasibility for total laryngectomy and cost-effectiveness makes it a promising option for wider adoption, particularly in low-resource settings.

Indexed as

head and neck cancerlaryngectomyminimally invasive surgeryTOUSStransoral surgeryultrasonic scalpel

Identifiers

PMID41403813
PMCPMC12631591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.