Evidence map›Paper›PMID 41403788›Full record

ArticleIJU case reports2026

A Case of Acquired Factor V Deficiency in a Hemodialysis Patient: A Case Report With Literature Review.

Akihiko Sugino, Yoshiyuki Miyazawa, Shugo Harashima, Yusaku Shimizu, Mikiya Kajita, Yuri Miyazawa, Yoshiyuki Ogawa, Hiroshi Handa, Yoshitaka Sekine, Kazuhiro Suzuki

Abstract read
In one paragraph

Article in IJU case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Akihiko SuginoDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0009-0001-5257-6293
Yoshiyuki MiyazawaDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0000-0002-8416-2394
Shugo HarashimaDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0009-0009-7142-8040
Yusaku ShimizuDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0009-0000-8887-0489
Mikiya KajitaDepartment of Hematology Gunma University Graduate School of Medicine Maebashi Gunma Japan.
Yuri MiyazawaDepartment of Hematology Gunma University Graduate School of Medicine Maebashi Gunma Japan.
Yoshiyuki OgawaDepartment of Hematology Gunma University Graduate School of Medicine Maebashi Gunma Japan.
Hiroshi HandaDepartment of Hematology Gunma University Graduate School of Medicine Maebashi Gunma Japan.
Yoshitaka SekineDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0000-0002-8094-4524
Kazuhiro SuzukiDepartment of Urology Gunma University Graduate School of Medicine Maebashi Gunma Japan.ORCID https://orcid.org/0000-0002-1448-7273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acquired factor V (FV) deficiency is a rare bleeding disorder requiring careful management, especially in hemodialysis (HD) patients who regularly receive anticoagulants. We present a case of recurrent acquired FV deficiency in a dialysis patient. Case Presentation: A 76-year-old man on HD with a history of acquired FV deficiency developed third-degree burns and persistent bleeding. Lab tests confirmed the recurrence of the deficiency. Initial treatments with rituximab and cyclophosphamide were ineffective. When prednisolone was rechallenged, the activity of coagulation FV was rapidly improved, and coagulation function was confirmed to have returned to normal. HD was managed without anticoagulants during critical periods. No major bleeding events were observed during HD. Conclusion: This case underscores the complexities of managing acquired FV deficiency in patients on HD. It highlights the importance of individualized anticoagulation strategies and close monitoring of coagulation profiles to prevent bleeding complications and ensure the safety of HD.

Indexed as

acquired factor V deficiencycoagulation abnormalityhemodialysis

Identifiers

PMID41403788
PMCPMC12704224

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.