Evidence map›Paper›PMID 41403711›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Effect of Social Determinants of Health and Geography on Uveal Melanoma.

Haarisudhan Sureshkumar, Srishti Kolla, Rohith Erukulla, Weiwei Ma, Reem Alahmadi, Jiehuan Sun, Michael J Heiferman

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haarisudhan SureshkumarDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.ORCID 0009-0001-1396-2642
Srishti KollaDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.
Rohith ErukullaDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.ORCID 0000-0002-4601-5756
Weiwei MaDivision of Epidemiology and Biostatistics, University of Illinois School of Public Health, Chicago, IL, USA.
Reem AlahmadiDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.
Jiehuan SunDivision of Epidemiology and Biostatistics, University of Illinois School of Public Health, Chicago, IL, USA.
Michael J HeifermanDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aims to examine the geographic distribution of ocular oncologists in the United States and evaluates how social determinants of health (SDOH) and environmental factors influence access to ocular oncologists nationally and uveal melanoma (UM) outcomes locally at the University of Illinois (UI) Hospital. Patients and Methods: A national analysis mapped ocular oncologist locations using ArcGIS Pro, assessing accessibility via drive-time radii (15-60 minutes) and census tract population density. SDOH variables (income, education, and insurance) were extracted from US Census data. A retrospective chart review of 167 UM patients at UI Hospital (2010-2023) analyzed tumor characteristics, referral patterns, and SDOH/environmental factors linked to zip codes. Statistical analyses included t-tests, logistic regression, and False Discovery Rate correction. Results: Nationally, 33.5% of the population, including 45.9% of rural residents, live beyond 60 minutes of an ocular oncologist. Areas outside of an accessible distance of an ocular oncologist were more likely to have low-income, less-educated, and uninsured populations (p < 0.001). At UI Hospital, patients outside a 60-minute radius required significantly more referrals (p = 0.046) but showed no differences in tumor stage at presentation. Trends suggested larger tumor thickness in areas with fewer naturalized citizens and more households under the Asset Limited, Income Constrained, Employed threshold. (q = 0.068 and q = 0.093, respectively). Environmental factors showed no significant associations, including Lifetime Inhalation Cancer Risk, Water Polluting Sites Environmental Justice Index, and Optometrists Per Capita. Conclusion: There may be geographic and socioeconomic barriers that limit access to UM care, particularly in rural and underserved communities. While proximity did not affect tumor presentation at UI Hospital, referral delays and socioeconomic trends highlight systemic inequities. Multicenter studies are needed to further explore these disparities and improve equitable UM care delivery.

Indexed as

barriers to caregeographysocial determinantsuveal melanoma

Identifiers

PMID41403711
PMCPMC12704188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.