ArticleRSC advances2025
A nanocarrier delivery system of oxaliplatin for glioblastoma: synthesis and cytotoxicity of Fe
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Synthesis and characterization of SPIONs@APTES conjugated with chlorin E6 via carbodiimide for photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among the available treatments for glioblastoma multiforme (GBM), chemotherapy is the most widely used because anticancer drugs can help shrink the tumour. Unfortunately, these drugs present several problems, such as the resistance of cancer cells, low specificity and secondary effects. Using nanocarriers for these drugs is a novel strategy that can reduce the side effects associated with chemotherapy, thereby enabling treatments that are less taxing on the body. In this study, nanocarriers based on superparamagnetic iron nanoparticles coated with silicon oxide were prepared, and the surface of the nanocomposite was functionalised with oxaliplatin, a drug commonly used in chemotherapy. FTIR, XRD, UV-Vis, TEM, and VSM techniques were employed for compositional, structural, morphological, and magnetic characterisation. FTIR confirmed the presence of iron oxide, silica, and oxaliplatin in the nanocomposites, while XRD and TEM analyses revealed the crystalline structure and size distribution of the nanoparticles. UV-Vis spectroscopy indicated the adsorption of oxaliplatin onto the nanoparticle surface, with a gradual increase in adsorption over time. The cytotoxicity of Fe
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Registered trials
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