Evidence map›Paper›PMID 41403609›Full record

ArticleArchives of medical science : AMS2025

A causal inference study on the impact of asthma on the onset of chronic obstructive pulmonary disease: two-sample Mendelian randomization.

Wusheng Liu, YuHui Xu, Zanlei Zhu, ShiHao Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wusheng LiuDepartment of Respiratory and Critical Care Medicine, Ganzhou People's Hospital, Zhanggong, Ganzhou, Jiangxi, China.
YuHui XuDepartment of Respiratory and Critical Care Medicine, Ganzhou People's Hospital, Zhanggong, Ganzhou, Jiangxi, China.
Zanlei ZhuDepartment of Respiratory and Critical Care Medicine, Ganzhou People's Hospital, Zhanggong, Ganzhou, Jiangxi, China.
ShiHao ZhangDepartment of Respiratory and Critical Care Medicine, Ganzhou People's Hospital, Zhanggong, Ganzhou, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Asthma and chronic obstructive pulmonary disease (COPD) are two common respiratory ailments with an overlapping pathogenesis. Material and methods: In this study, using a two-sample Mendelian randomization (MR) approach and analyzing publicly available genome-wide association study (GWAS) datasets, we explored the causal impact of asthma on the onset of COPD. Results: Results: Using genetic instrumental variables associated with asthma ( Conclusions: This study provides robust evidence supporting the causal link between asthma and COPD, offering a more comprehensive understanding of their relationship.

Indexed as

asthmacausal relationshipchronic obstructive pulmonary diseaseenvironmental exposure factorsgenome-wide association studyMendelian randomization

Identifiers

PMID41403609
PMCPMC12703613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.