ArticleHealth science reports2025
Beyond the Autoimmune Spectrum, Evaluating Ovarian Health in Systemic Lupus Erythematosus Patients: A Case-Control Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Beyond the Autoimmune Spectrum, Evaluating Ovarian Health in Systemic Lupus Erythematosus Patients: A Case-Control Study.Health science reports · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, and recent findings reveal that fertility and ovarian reserve are reduced even in moderate illness, showing that SLE has a direct impact on ovarian function. Therefore, this study aimed to evaluate ovarian reserve using Anti-Müllerian hormone (AMH) and antral follicle count (AFC) in SLE patients compared to healthy controls. Methods: This case-control study was performed on 300 cases (150 SLE patients and 150 healthy controls). For evaluating ovarian reserve, AMH and AFC were evaluated. Furthermore, SLE activity was determined through the employment of the SLEDAI-2k questionnaire. Results: Findings revealed that the mean serum levels of AMH were significantly lower in the SLE group as compared to healthy controls (1.34 ± 1.16 vs. 2.47 ± 1.48 ng/mL, Conclusions: According to the results of the present study, young women with SLE should check their ovarian reserve regularly, and both AMH and AFC should be evaluated periodically because ovarian reserve may be reduced faster in SLE cases.
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