ReviewJournal of family medicine and primary care2025
The top 50 cited publications in the field of vitamin B12 deficiency: A bibliometric analysis review.
Review in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Vitamin B12 deficiency is a significant nutritional concern linked to megaloblastic anemia and neurological complications, and high-quality research is essential to address these health issues effectively. While highly cited publications have substantial influence on the field, there remains a need to assess the methodological rigor, research trends, and quality of these impactful studies. This bibliometric analysis aims to evaluate the top 50 most-cited articles on Vitamin B12 deficiency, with a focus on identifying research gaps, trends, and areas for future investigation. Methodology: A comprehensive literature search was conducted in the Web of Science database to identify the 50 most-cited articles on Vitamin B12 deficiency. Key terms included MeSH headings and keywords related to Vitamin B12 deficiency, and articles were included based on criteria such as peer-reviewed status, citation count, and focus on human subjects. Data extraction covered publication details (year, country, and journal), study characteristics (design, primary topic), and citation information. The selected articles were analyzed for authorship patterns, country contributions, study design distribution, and research topics to evaluate trends and gaps within the field. Results: The analysis revealed a predominance of research originating from developed countries, with the US contributing 44% of the top-cited studies, followed by the UK at 16%. The most common study design was the review article (56%), and the highest level of evidence achieved was Level 1 in 14% of studies. Research topics primarily focused on management (38%), causes (36%), and diagnosis (32%) of Vitamin B12 deficiency. A gender disparity was noted in authorship, with male senior authors representing 62% of the studies. Conclusion: This bibliometric analysis highlights the need for more diverse and experimental research approaches in Vitamin B12 deficiency studies, particularly from underrepresented regions. The reliance on observational and review-based designs suggests an opportunity for more rigorous methodologies, such as RCTs, to enhance the evidence base.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.