Evidence map›Paper›PMID 41403428›Full record

ArticleERJ open research2025

Noninvasive respiratory support for preoxygenation in emergency intubation: a systematic review and network meta-analysis.

Annalisa Boscolo, Nicolò Sella, Tommaso Pettenuzzo, Elisa Pistollato, Francesco Zarantonello, Sebastiano Ongaro, Francesco Monteleone, Francesca Medici, Paola Zanon, Alessandro Zambianchi and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Annalisa BoscoloDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Nicolò SellaInstitute of Anesthesia and Intensive Care, Padova University Hospital, Padua, Italy.
Tommaso PettenuzzoInstitute of Anesthesia and Intensive Care, Padova University Hospital, Padua, Italy.
Elisa PistollatoDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Francesco ZarantonelloInstitute of Anesthesia and Intensive Care, Padova University Hospital, Padua, Italy.
Sebastiano OngaroDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Francesco MonteleoneDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Francesca MediciDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Paola ZanonDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Alessandro ZambianchiDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Serafino TalaricoDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Annachiara CremoneDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Giulia MormandoDIMED, University of Padova, Padua, Italy.
Honoria OcagliUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padua, Italy.
Alessandro De CassaiDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.
Dario GregoriUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padua, Italy.
Samir JaberDepartment of Anesthesiology and Critical Care Medicine B (DAR B), Sant-Eloi Hospital, University Teaching Hospital of Montpellier, Montpellier, France.
Paolo NavalesiDepartment of Medicine (DIMED), Section of Anaesthesiology and Intensive Care, University of Padova, Padua, Italy.ORCID https://orcid.org/0000-0002-3733-3453
PADOVA ICU Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The benefits of preoxygenation with noninvasive respiratory support (NRS), including high-flow oxygen therapy (HFOT) and noninvasive ventilation (NIV), compared to conventional oxygen therapy (COT) during emergency endotracheal intubation (ETI) remain unclear. This network meta-analysis aims to evaluate whether preoxygenation with NRS is more effective than COT in minimising the lowest recorded peripheral capillary oxygen saturation ( Methods: A comprehensive literature search was conducted (PROSPERO-CRD42024606842) across Medline, Embase and Scopus. The PICOS criteria were: P: critically ill adult patients requiring emergency ETI; I: randomisation for receiving preoxygenation with NRS; C: randomisation for COT; O: the lowest recorded Results: 15 RCTs (2939 patients) met the inclusion criteria. Compared to COT, all NRS methods improved the lowest Interpretation: During emergency ETI in critical care areas, despite a low certainty of evidence, preoxygenation with NRS overperformed COT in maintaining

Identifiers

PMID41403428
PMCPMC12704149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.