ArticleERJ open research2025
Breathomics in controlled asthma: identification of nonanoic and propanoic acids as volatile organic compounds.
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- A circulating odd-chain fatty acid biomarker signature discriminates pediatric allergic rhinitis with asthma from related allergic airway phenotypes.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There is growing interest in identifying novel, non-invasive biomarkers reflecting endogenous inflammatory processes in asthma. This study aimed to evaluate the presence of volatile organic compounds (VOCs) in exhaled breath from patients with clinically controlled asthma and assess how tobacco exposure influences their expression. Methods: Exhaled breath samples from 120 clinically controlled asthma patients and 89 healthy controls were collected using BioVOC breath samplers. Samples were analysed by gas chromatography-mass spectrometry, assessing five previously characterised VOCs: hexanal, heptanal, nonanal, propanoic acid and nonanoic acid. Results: Compared to healthy controls, asthma patients exhibited a lower frequency of propanoic acid exhalation (25.0% Conclusions: Exhaled propanoic and nonanoic acids may serve as complementary non-invasive biomarkers for monitoring controlled asthma, independently of tobacco exposure. VOC analysis has promising potential to improve asthma management, therapeutic monitoring and patient stratification.
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Registered trials
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