Evidence map›Paper›PMID 41403091›Full record

ArticleRenal failure2025

Zhenwu decoction ameliorates adriamycin-induced nephrotic syndrome in rats via dual modulation of AVP-V2R-AQP2 and RAAS-MR-AQP3 pathways.

Mengmeng Xu, Min Du, Wanying Qu, Yanjun Wei, Hui Wang, Xin Yang

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengmeng XuSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Min DuDepartment of Gastroenterology, First Affiliated Hospital of Guizhou, University of Traditional Chinese Medicine, Guiyang, China.
Wanying QuSchool of Health Preservation, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Yanjun WeiSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Hui WangSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Xin YangSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The core bioactive components of Zhenwu Decoction (ZWD)-utilized for managing kidney diseases-and the associated anti-nephrotic syndrome (NS) edema mechanism remain incompletely characterized. We assessed the potential mechanism of ZWD against adriamycin (ADR)-induced NS. Sprague-Dawley rats (

Indexed as

Drugs, Chinese HerbalNephrotic SyndromeRenin-Angiotensin SystemAnimalsAquaporin 2Disease Models, AnimalDoxorubicinKidneyMaleRatsRats, Sprague-DawleyReceptors, MineralocorticoidSignal TransductionAqp2 protein, ratAquaporin 2DoxorubicinDrugs, Chinese HerbalReceptors, Mineralocorticoiddoxorubicin nephropathynephrotic syndromerenal fibrosisRenin-Angiotensin-Aldosterone system (RAAS)traditional chinese medicine (TCM)Zhenwu decoction

Identifiers

PMID41403091
PMCPMC12713216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.