Evidence map›Paper›PMID 41403072›Full record

SynthesisAnnals of medicine2025

Gait differences after ACL reconstruction versus healthy controls: a three-level meta-analysis of kinematics, kinetics, and spatiotemporal parameters.

Shiwei Chen, Wenling Gou, Renzhi Gao

Abstract readMeta-Analysis
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shiwei ChenLeshan Vocational and Technical College, Leshan, China.ORCID 0009-0005-2919-4667
Wenling GouFaculty of Physical and Sports Sciences and Techniques, University of Montpellier, Montpellier, France.ORCID 0009-0007-6199-4407
Renzhi GaoDepartment of Orthopedics, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, China.ORCID 0000-0002-9484-396X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis meta-analysis was designed to evaluate whether individuals following ACL reconstruction exhibit normalized gait biomechanics when compared to healthy controls.

methodsThis review was conducted across five databases: PubMed, Embase, The Cochrane Library, Web of Science and EBSCOhost-SportDiscus, yielding a total of 5,251 records, with 21 qualified studies (52 independent samples from 861 participants; based on available data, the mean age was 26.5 ± 4.3 years and 51.3% were female) eligible for quantitative synthesis following rigorous screening. A three-level meta-analysis model was implemented to address effect size dependencies. Six gait parameters were analyzed, including kinematic variables (peak knee flexion and extension angles during stance), kinetic variables (peak external knee flexion and extension moments during stance) and spatiotemporal variables (stride length and walking speed).

resultsAmong the six gait parameters that were analyzed, only the peak knee extension angle during stance (

conclusionThis meta-analysis shows that the majority of gait parameters during stance, including peak knee flexion angle, external knee flexion and extension moments, stride length and walking speed, do not differ significantly between individuals with ACL reconstruction and healthy controls. Only peak knee extension angle remained impaired, though it showed signs of improvement over time. Persistent knee extension deficits emphasize the need for targeted quadriceps and knee control training as a key focus for long-term ACLR rehabilitation.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionGaitAdultBiomechanical PhenomenaFemaleHumansKineticsKnee JointMaleRange of Motion, Articularfunctional recoverygait adaptationlong-term rehabilitationPostoperative recoverythree-level modelling

Identifiers

PMID41403072
PMCPMC12713220

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.