Evidence map›Paper›PMID 41403059›Full record

ArticleACS chemical biology2026

Seth D Veenbaas, Simon Felder, Kevin M Weeks

Abstract read
In one paragraph

Article in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

3 authors.

Seth D VeenbaasDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, United States.
Simon FelderDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, United States.ORCID 0000-0001-5146-5340
Kevin M WeeksDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, United States.ORCID 0000-0002-6748-9985

Funding

Non-coding RNA structure change in Chronic Obstructive Pulmonary DiseaseR01HL111527 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alain T Laederach, Kevin M Weeks · 2012 to 2026
$6.6M
Translational regulation by covalent modification of mRNAR21AG084970 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEEKS, KEVIN M · 2023 to 2023
$426k
NHLBI NIH HHS R01 HL111527NIA NIH HHS R21 AG084970
6 · The paper itself

Abstract

Small molecules that bind specific sites in RNAs hold promise for altering RNA function, manipulating gene expression, and expanding the scope of druggable targets beyond proteins. Identifying binding sites in RNA that can engage ligands with good physicochemical properties remains a significant challenge.

Indexed as

RNASoftwareBinding SitesLigandsModels, MolecularNucleic Acid ConformationLigandsRNA

Identifiers

PMID41403059
PMCPMC12904495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.