Evidence map›Paper›PMID 41402896›Full record

ArticleBMC sports science, medicine & rehabilitation2025

Comparative efficacy of myofascial release versus stretching combined with high-powered pulsed therapeutic ultrasound in amateur overhead athletes with active trapezius trigger point pain: a randomized clinical trial.

Nizamuddin Khan, Tushita Ghai, Richa Kashyap, Priyadarshani Bhat, Fuzail Ahmad, Amir Iqbal, Talal Alghadir, Faisal Alghadir, Shahnawaz Anwer, Ahmad H Alghadir

Registry-linked trialAbstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07002593 (Comparative Efficacy of Myofascial Release Versus Stretching Combined With High-Powered Pulsed Therapeutic Ultrasound in Athletes With Active Trapezius Trigger Points), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07002593 nacompletednot on this map

Comparative Efficacy of Myofascial Release Versus Stretching Combined With High-Powered Pulsed Therapeutic Ultrasound in Athletes With Active Trapezius Trigger Points: A Randomized Comparative Trial

TypeinterventionalSponsorKing Saud UniversityRan2022 to 2023Enrolled54ConditionsActive Trapezius Trigger Point PainArmsMyofascial release (MFR), Muscle Stretching, High-powered pulsed therapeutic ultrasound (HPPT-US)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nizamuddin KhanDepartment of Physiotherapy, Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences, Chaudhary Charan Singh University (Meerut), Greater Noida, 201310, Uttar Pradesh, India.
Tushita GhaiDepartment of Physiotherapy, Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences, Chaudhary Charan Singh University (Meerut), Greater Noida, 201310, Uttar Pradesh, India.
Richa KashyapDepartment of Physiotherapy, ITS College of Health & Wellness Sciences, Atal Bihari Vajpayee Medical University, Greater Noida, 201310, Uttar Pradesh, India.
Priyadarshani BhatDepartment of Physiotherapy, ITS College of Health & Wellness Sciences, Atal Bihari Vajpayee Medical University, Greater Noida, 201310, Uttar Pradesh, India.
Fuzail AhmadRespiratory Care Department, College of Applied Sciences, Almaarefa University, Diriyah, Riyadh, 13713, Saudi Arabia.
Amir IqbalRehabilitation Research Chair, Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, P.O. BOX. 10219, Riyadh, 11433, Saudi Arabia. physioamir@gmail.com.ORCID http://orcid.org/0000-0002-9080-367X
Talal AlghadirCollege of Medicine, King Saud University, Riyadh, 11433, Saudi Arabia.
Faisal AlghadirCollege of Medicine, King Saud University, Riyadh, 11433, Saudi Arabia.
Shahnawaz AnwerDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
Ahmad H AlghadirRehabilitation Research Chair, Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, P.O. BOX. 10219, Riyadh, 11433, Saudi Arabia.

Funding

Ongoing Research Funding program - Research Chairs (ORF-RC-2025-1000), King Saud University, Riyadh, Saudi Arabia. ORF-RC-2025-1000
6 · The paper itself

Abstract

backgroundActive myofascial trigger points (MTrPs) in the upper trapezius are a leading source of neck pain and functional limitation in athletes. Although myofascial release (MFR) and stretching are frequently used, their comparative effectiveness when combined with high-power pulsed therapeutic ultrasound (HPPT-US) remains unclear.

objectiveTo compare the efficacy of MFR + HPPT-US versus stretching + HPPT-US on pain intensity, cervical range of motion (Cx-ROM), muscle length (ML), and neck disability in amateur overhead athletes with unilateral upper trapezius active MTrPs. Trial design: A two-arm parallel group, randomized clinical trial design.

methodsThirty-two athletes meeting Travell and Simons’ criteria for active MTrPs were randomized to receive either MFR + HPPT-US (Group A) or stretching + HPPT-US (Group B), administered thrice weekly for two weeks. Primary outcome measure—Pain intensity and secondary outcomes—Cx-ROM, ML, and Neck Disability Index (NDI) were recorded using a visual analog scale (VAS), universal goniometer, Vernier caliper, and neck disability index (NDI) questionnaire, at baseline, week 1, week 2, and one-week follow-up. 26 out of 32 data of enrolled participants were analyzed using a two-way mixed repeated-measures ANOVA (Group × Time) with Bonferroni-adjusted post-hoc tests; statistical significance was set at p < 0.05, and effect sizes were reported as partial eta-squared (η²ₚ) for ANOVA and Cohen’s d for pairwise differences.

resultsSignificant main effects of Group (η²ₚ = 0.07–0.26) and Time (η²ₚ = 0.83–0.92) were observed for all outcomes, with a significant Group × Time interaction for ML (η²ₚ = 0.34). Both interventions produced significant improvements across time points; however, Group A demonstrated greater gains following treatment. At follow-up, between-group differences favored Group A for VAS (MD = − 0.77; 95% CI − 1.31 to − 0.39; d = 1.12), Cx-ROM (MD = 2.69°; 95% CI 0.80 to 4.58; d = 1.07), ML (MD = 0.80 cm; 95% CI 0.27 to 1.33; d = 1.14), and NDI (MD = − 4.70; 95% CI − 8.04 to − 1.36; d = 1.09). Improvements were consistent across post-baseline assessments, although the magnitude of change varied by outcome.

conclusionThe combination of MFR and HPPT-US was more effective than stretching with HPPT-US in reducing pain, increasing ML and Cx-ROM, and improving functional outcomes in amateur overhead athletes with active upper trapezius MTrPs. This combined approach may offers superior clinical benefits for managing MTrP-related neck pain and promoting faster recovery in athletic rehabilitation settings.

trial registrationThe study protocol was retrospectively registered to the “ClinicalTrials.gov” under an assigned Identifier: NCT07002593 on 25/05/2025 ( https://clinicaltrials.gov/study/NCT07002593 ).

Indexed as

AthletesMyofascial pain syndromesRange of motionTrigger pointsUltrasonic therapy

Identifiers

PMID41402896
PMCPMC12911243

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.