Evidence map›Paper›PMID 41402788›Full record

ArticleBMC cancer2025

Preliminary study for the development of enhanced recovery after surgery program for free flap reconstruction in older population with advanced oral cancer: a single-center retrospective study.

Fumitaka Obayashi, Koichi Koizumi, Nanako Ito, Mirai Higaki, Atsuko Hamada, Sachiko Yamasaki, Yumio Fujioka, Shogo Nagamatsu, Isao Koshima, Souichi Yanamoto

Abstract read
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In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fumitaka ObayashiDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan. fumi2390@hiroshima-u.ac.jp.
Koichi KoizumiDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Nanako ItoDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Mirai HigakiDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Atsuko HamadaDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Sachiko YamasakiDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Yumio FujiokaDepartment of Plastic and Reconstructive Surgery, Hiroshima University Hospital, Hiroshima, Japan.
Shogo NagamatsuDepartment of Plastic and Reconstructive Surgery, Hiroshima University Hospital, Hiroshima, Japan.
Isao KoshimaDepartment of Plastic and Reconstructive Surgery, Hiroshima University Hospital, Hiroshima, Japan.
Souichi YanamotoDepartment of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe enhanced recovery after surgery (ERAS) program is a combined perioperative bundle designed to reduce perioperative stress. However, whether these programs are safe and effective for older patients who have undergone free-flap reconstruction for locally advanced oral cancers remains unclear. This study retrospectively evaluated the risk factors associated with delayed postoperative recovery and prolonged hospital length of stay (LOS) in older patients with locally advanced oral cancer who underwent resection and free-flap reconstruction from an ERAS perspective.

methodsSixty-one patients who underwent resection and free-flap reconstruction for locally advanced oral cancer were included. LOS, complications, nutritional intake, and mobilization were evaluated.

resultsThe older group exhibited a longer LOS, delayed oral feeding, and more aspiration pneumonia than the non-older group. Analysis of older adults only revealed delayed oral feeding, not chronological age, as a risk factor for prolonged LOS.

conclusionsOlder patients were safely managed using ERAS; however, dysphagia may have interfered with the enhanced recovery.

Indexed as

Enhanced Recovery After SurgeryFree Tissue FlapsMouth NeoplasmsPlastic Surgery ProceduresAgedAged, 80 and overFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsEnhanced recovery after programFree flap reconstructionOral cancer

Identifiers

PMID41402788
PMCPMC12709736

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.