Evidence map›Paper›PMID 41402731›Full record

ArticleGenetics, selection, evolution : GSE2025

Characterization of genomic diversity and population structure of worldwide Duroc subpopulations and other pig breeds.

Hui Wen, Harvey D Blackburn, Henrique A Mulim, Hinayah R Oliveira, Susanne Hermesch, Ching-Yi Chen, Justin Holl, Allan P Schinckel, Luiz F Brito

Abstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui WenDepartment of Animal Sciences, Purdue University, IN, 47907, West Lafayette, USA.
Harvey D BlackburnUSDA ARS National Animal Germplasm Program, 1111 S. Mason St, CO, 80521, Fort Collins, USA.
Henrique A MulimDepartment of Animal Sciences, Purdue University, IN, 47907, West Lafayette, USA.
Hinayah R OliveiraDepartment of Animal Sciences, Purdue University, IN, 47907, West Lafayette, USA.
Susanne HermeschAGBU, a joint venture of NSW Department of Primary Industries and University of New England, Armidale, NSW, 2351, Australia.
Ching-Yi ChenGenus PIC, Hendersonville, TN, 37075, USA.
Justin HollGenus PIC, Hendersonville, TN, 37075, USA.
Allan P SchinckelDepartment of Animal Sciences, Purdue University, IN, 47907, West Lafayette, USA.
Luiz F BritoDepartment of Animal Sciences, Purdue University, IN, 47907, West Lafayette, USA. britol@purdue.edu.ORCID http://orcid.org/0000-0002-5819-0922

Funding

Agricultural Research Service 58-3012-2-024
6 · The paper itself

Abstract

backgroundDuroc is one of the most popular terminal sire pig breeds worldwide due to its greater growth rate, meat quality, feed efficiency, and carcass characteristics compared to other breeds. Despite the breed's popularity, its developmental history, genetic diversity, and genetic relationships with other pig breeds remain largely unknown. Therefore, the primary objective of this study was to investigate population structure and genetic diversity of Duroc subpopulations from Europe, North America, and Australia, and of other pig breeds.

resultsThe studied pig populations were differentiated into five subgroups(European and North American Durocs, Australian Durocs, Asian-Pacific pig breeds, and two other breed groups [OBP1 and OBP2]), consistent with their geographical origins, as revealed by population structure analyses. The estimated effective population size (Ne) of Duroc subpopulations ranged from 17 to 47, while the Ne for the combined Duroc subpopulations was 172. A total of 140,713 runs of homozygosity (ROHs) were identified across all individuals, with 98,039 ROHs in Durocs and 42,674 in other pig breeds. Durocs had a greater number and proportion of longer ROHs (> 8 Mb) compared to other pig breeds. The ROH-based inbreeding (F

conclusionsSignificant differences exist in genetic diversity, population structure, and ancestry within Duroc subpopulations and between Duroc and other pig breeds. The observed inbreeding levels in Duroc subpopulations indicate the need for better management of genetic diversity within the breed. Functional enrichment analyses of shared ROH islands provide new insights into biological pathways shaped by selection decisions in the past decades, especially those related to the immune system and energy metabolism.

Indexed as

Genetic VariationSus scrofaAnimalsAustraliaBreedingGenetics, PopulationGenomeHomozygoteInbreedingPolymorphism, Single NucleotideSwine

Identifiers

PMID41402731
PMCPMC12781363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.