Observational studyBMC gastroenterology2025
Days alive and out of hospital at 90 days as a composite outcome measure in patients undergoing elective surgery for colorectal cancer- a nationwide, observational study.
Observational study in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Time toxicity in cancer care: a systematic review of definitions and measurement methods.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Days Alive and out of Hospital at 30 Days After Curative Gastrectomy for Gastric Adenocarcinoma: Complication-Severity Gradient and Readmission Burden.Journal of clinical medicine · 2026Article
- Preoperative Frailty Assessed by the Record-Based Multidimensional Prognostic Index Predicts 90-Day Days Alive and out of Hospital Following Radical Cystectomy for Bladder Cancer: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate the validity of DAOH-90 in a contemporary cohort of electively operated patients with colorectal cancer and explore its relationship with postoperative outcomes.
designThe study was a retrospective, observational cohort study. SETTINGS: Data on patients operated from April 2014 to April 2019 were collected from the Danish Colorectal Cancer Group database and enriched by information from the Danish National Patient Register. DAOH-90 was analyzed by quantile regression for the 10th, 25th, 50th, 75th, and 90th percentile, using Mann-Whitney U-test, and association between DAOH-90 and 1-and 5-year mortality was analyzed using a Cox regression. PATIENTS: A total of 16,183 patients with colorectal cancer were included. Median DAOH-90 was 85 (IQR: 82-87). The 90-day mortality was 2.2%.
main outcome measuresThe primary outcome was the association between DAOH-90 quantiles and long-term mortality (1 and 5 years).
resultsThere was significant association between DAOH-90 in the 25th, 50th and 75th quantile and death between 90 and 365 days (p = 0.0008-< 0.0001), and for death between 1 and 5 years (p = 0.0026-p < 0.0001). Both medical and surgical complications were associated with significantly lower DAOH-90 for all percentiles. The multivariable quantile regression confirmed that notably complications and poor performance status had great impact on DAOH-90.
conclusionDAOH-90 was associated with several demographic and comorbidity related variables, including severe surgical complications. DAOH-90 was also associated with long-term mortality.
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