Evidence map›Paper›PMID 41402688›Full record

ArticleAnnals of surgical oncology2026

Assessing Clinical Factors and Communication Barriers Impacting Postoperative Regret in Patients with Pancreatic Cancer.

Judy Li, Thomas M Li, Adam Geffner, Sophie Neugarten, Camilo Correa-Gallego, Joshua Leinwand, Neha L Lad, Ganesh Gunasekaran, Spiros Hiotis, Myron E Schwartz and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Judy LiDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Thomas M LiDepartment of Surgery, University of California San Francisco, San Francisco, CA, USA.
Adam GeffnerDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sophie NeugartenDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Camilo Correa-GallegoDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Joshua LeinwandDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Neha L LadDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ganesh GunasekaranDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Spiros HiotisDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Myron E SchwartzThe Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Parissa TabrizianThe Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Umut SarpelDivision of Surgical Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Daniel M LabowDivision of Surgical Oncology, Department of Surgery, Nuvance Health, Danbury, CT, USA.
James O ParkDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Noah A CohenDivision of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Noah.Cohen@mountsinai.org.ORCID http://orcid.org/0000-0003-3947-2585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurative-intent pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) carries high rates of morbidity and recurrence. Patients with operable PDAC face a complex decision of whether to pursue resection. Factors impacting the decision-making process and decisional regret (DR) are relatively unexplored. PATIENTS AND

methodsPatients with PDAC who underwent curative-intent pancreatectomy at least 6 months prior to study recruitment completed validated surveys assessing DR, health literacy, shared decision-making, and quality of life.

resultsOverall, 60 patients (48% female) completed all surveys. Postoperative DR (DRS > 1) was reported in 21 (35%) patients. The median time from surgery to survey completion was 55 months in the DR Present group and 33 months in the DR Absent group (P = 0.895). Receipt of systemic therapy, operative characteristics, and postoperative course were similar between groups. The DR Present group had lower rates of obtaining advanced educational degrees (48% versus 76%, P = 0.031), lower health literacy (BRIEF score 14.8 ± 4.2 versus 17.0 ± 2.5, P = 0.014), and greater discordance between preferred and actual roles in the decision making process (Cohen's kappa 0.672 [95% CI 0.530-0.814] versus 0.912 [95% CI 0.852-0.972], P < 0.001). The DR Present group reported worse physical ability (EORTC score 77.8 ± 21.8 versus 91.3 ± 11.8, P = 0.014), functional role (EORTC score 63.5 ± 33.2 versus 85.5 ± 27.6, P = 0.008), and social activity (EORTC score 65.9 ± 35.9 versus 85.9 ± 21.4, P = 0.026) scores.

conclusionsLower health literacy and discordance in preferred and actual decision-making roles negatively impacts post-pancreatectomy DR. Adequate preoperative counseling on potential quality of life changes is critical for informed decision-making.

Indexed as

Carcinoma, Pancreatic DuctalCommunication BarriersDecision MakingEmotionsPancreatectomyPancreatic NeoplasmsQuality of LifeAgedDecision Making, SharedFemaleFollow-Up StudiesHealth LiteracyHumansMaleMiddle AgedPrognosisHealth literacyPancreatic cancerPostoperative regretQuality of lifeShared decision-making

Identifiers

PMID41402688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.