ArticleLasers in medical science2025
Tightening of the eyelids with monopolar radiofrequency in Asians.
Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Objective and subjective retrospective evaluation of XERF, a novel single-shot dual-frequency non-invasive monopolar radiofrequency.Lasers in medical science · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Eyelid laxity is a visible sign of aging that can significantly affect appearance and comfort; however, many patients remain reluctant to undergo surgical blepharoplasty. Monopolar radiofrequency (RF) offers a non-invasive alternative. This study evaluated the efficacy and safety of a 0.25 cm² monopolar RF tip for upper eyelid tightening in Asians. Fourteen subjects received a single session of treatment with a 0.25 cm² tip monopolar RF device. Multiple passes were applied to the upper eyelid and lateral orbital regions. Topical anesthesia was applied 30 min before treatment, and a protective plastic contact lens was used during the procedure. Standardized digital photography, physician assessments, and patient-reported outcomes were obtained at each visit. All subjects demonstrated clinical improvement. At 2 months, 73% of patients reported more than 50% improvement in eyelid tightening, increasing to 86% at 6 months. Physician Global Aesthetic Improvement Scale (GAIS) ratings corresponded to "much improved" at both time-points. Mid-pupillary brow elevation increased by 1.18 mm at 2 months and 1.45 mm at 6 months. Lateral canthal brow elevation increased by 1.23 mm and 1.21 mm, respectively. Superior palpebral crease elevation improved by 0.54 mm and 0.41 mm, while the eyebrow angle decreased by - 4.12° and - 5.67°, indicating a more elevated brow contour. No adverse events were observed. In conclusion, monopolar RF treatment with a 0.25 cm² tip appears to be a safe and effective non-surgical option for upper eyelid tightening in Asians.
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