Evidence map›Paper›PMID 41402554›Full record

ArticlePflugers Archiv : European journal of physiology2025

When does the "third fluid space" open?

Robert G Hahn

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert G HahnKarolinska Institutet at Danderyds Hospital (KIDS), Stockholm, 171 77 , Sweden. robert.hahn@ki.se.ORCID 0000-0002-1528-3803

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent kinetic studies show that the interstitial space contains two functional fluid compartments. This study explores the prerequisites for accumulation of infused crystalloid fluid in the remote slow-exchange space ("third fluid space¨, V

Indexed as

Extracellular FluidAdultCrystalloid SolutionsFemaleFluid TherapyHumansInfusions, IntravenousMaleMiddle AgedYoung AdultCrystalloid SolutionsCrystalloid fluid, pharmacokineticsHemodilutionInterstitial fluidWater–electrolyte balance, physiology

Identifiers

PMID41402554
PMCPMC12708698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.