Evidence map›Paper›PMID 41402128›Full record

ArticleInternational journal of spine surgery2026

Epidural Transforaminal Infraneural Infiltration Using Corticosteroids in Lumbar Radiculopathy.

Francisco de Assis Ulisses Sampaio Júnior, Francisco Ricardo Borges Ribeiro, Hetevaldo Tavares de Lira Filho, Oscar L Alves, Bartolomeu Souto Queiroz Quidute, Kaio Rodrigo Barreto Ramiro, Lucas de Souza Rodrigues Dos Santos, Mateus de Sousa Rodrigues

Abstract read
In one paragraph

Article in International journal of spine surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francisco de Assis Ulisses Sampaio JúniorSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Francisco Ricardo Borges RibeiroSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Hetevaldo Tavares de Lira FilhoSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Oscar L AlvesNeurosurgery Department, Hospital Lusíadas Porto, Porto, Portugal.
Bartolomeu Souto Queiroz QuiduteSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Kaio Rodrigo Barreto RamiroSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Lucas de Souza Rodrigues Dos SantosSpine Department, Sirio-Libanês Hospital, São Paulo, Brazil.
Mateus de Sousa RodriguesNeurosurgery Department, Restauração Hospital, Recife, Brazil mateus.kamloops@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA lumbar disc herniation is the primary cause of sciatica, affecting 1% to 5% of the population annually. Epidural corticosteroid injections, whether via the transforaminal or interlaminar route, are an option for patients with refractory sciatica pain. The transforaminal route has the advantage of directly addressing the site of pathology in the anterior epidural space, between the disc herniation and the nerve root. PURPOSE: To evaluate the efficacy of transforaminal infraneural epidural injections using corticosteroids in the treatment of radiculopathy secondary to acute lumbar disc herniation. STUDY

designDescriptive, nonrandomized, retrospective, and uncontrolled single-center study. PATIENT SAMPLE: Patients with radiculopathy secondary to acute lumbar disc herniation who underwent transforaminal epidural infiltrations between 2022 and 2024 were included.

main outcome measuresEfficacy of transforaminal infraneural epidural injections using corticosteroids in the treatment of radiculopathy secondary to acute lumbar disc herniation.

methodsThe inclusion criteria were (1) patients with onset of radiculopathy symptoms in the lower limbs less than 12 weeks prior; (2) patients with persistent radiculopathy symptoms in the lower limbs for more than 8 weeks; (3) clinical signs and symptoms of radiculopathy; (4) lumbar spine magnetic resonance imaging showing discopathy compatible with the clinical examination; and (5) minimum age of 18 years. From a technical standpoint, the entire procedure was performed in the operating room with sedation and local anesthesia.

conclusionsRadicular blocks are minimally invasive forms of treatment for radiculopathy refractory to medication-based analgesia due to an acute lumbar disc herniation. Transforaminal blocks offer the advantage of providing analgesia with a smaller amount of corticosteroid and represent a nonsurgical alternative that appears to be effective in treating radiculopathy secondary to acute lumbar disc herniation. CLINICAL RELEVANCE: This study highlights that infraneural transforaminal epidural steroid injection provides effective analgesia for acute lumbar radiculopathy secondary to disc herniation while using a smaller corticosteroid dose. This approach may help reduce systemic exposure and procedural risks, offering a safer alternative for patients requiring minimally invasive pain management. LEVEL OF EVIDENCE: 3:

Indexed as

lumbar disc herniationlumbar painradiculopathytransforaminal epidural injection

Identifiers

PMID41402128
PMCPMC13036458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.