Evidence map›Paper›PMID 41401907›Full record

ArticleNeurotoxicology and teratology

Gestational and early childhood air pollution exposure and neurodevelopmental outcomes in early childhood.

Christina Berninger, Yingying Xu, Patrick Ryan, Kim M Cecil, Bruce P Lanphear, Aimée Vester, Kimberly Yolton

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christina BerningerPeabody College of Education and Human Development, Vanderbilt University, Nashville, TN, USA; Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Yingying XuDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Patrick RyanDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Kim M CecilDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Bruce P LanphearDepartment of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
Aimée VesterDivision of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kimberly YoltonDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address: Kimberly.Yolton@cchmc.org.

Funding

Study of Prevalent Neurotoxicants in ChildrenP01ES011261 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI LANPHEAR, BRUCE P · 2001 to 2006
$6.4M
Longitudinal Impact of Air Pollution on Mental Health and Neuroimaging Outcomes during Adolescence in the Cincinnati Combined Childhood Cohorts (C4)R01ES031621 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI CECIL, KIM M, RYAN, PATRICK H · 2021 to 2025
$5.3M
A Community-Based Trial to Prevent Lead Poisoning and InjuriesR01ES014575 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI YOLTON, KIMBERLY · 2007 to 2011
$2.9M
NIEHS NIH HHS P01 ES011261NIEHS NIH HHS R01 ES014575NIEHS NIH HHS R01 ES031621
6 · The paper itself

Abstract

backgroundExposure to ambient air pollution, including fine particulate matter (PM

objectiveThis study examined the associations between gestational and early childhood exposures to PM

methodsIn the Health Outcomes and Measures of the Environment (HOME) Study, a longitudinal pregnancy and birth cohort, we used spatiotemporal models to estimate the concentration of each air pollutant at participants' home addresses during early brain development. Neurodevelopmental outcomes were measured using the Bayley Scales of Infant Development, Second Edition (BSID-II) at ages 1, 2, and 3 years. For 329 children, we examined the associations of air pollution with BSID-II scores using generalized linear models with generalized estimating equations (GEE).

resultsGestational and early childhood NO DISCUSSION: These results suggest that exposure to traffic-related air pollution during gestation and after birth may impact neurodevelopment in early childhood.

Indexed as

Air PollutantsAir PollutionChild DevelopmentEnvironmental ExposureNitrogen DioxideParticulate MatterPrenatal Exposure Delayed EffectsChild, PreschoolFemaleHumansInfantLongitudinal StudiesMalePregnancyAir PollutantsNitrogen DioxideParticulate MatterAir pollutionEarly childhoodFine particulate matterNeurodevelopmentNitrogen dioxidePostnatalPrenatal

Identifiers

PMID41401907
PMCPMC12857618

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.