ReviewMusculoskeletal science & practice2026
Neuro-immune contributors to persistent musculoskeletal pain: from mechanisms to clinical assessment and management.
Review in Musculoskeletal science & practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sex-specific molecular signatures in persistent pain after whiplash injury: an exploratory analysis.Pain reports · 2026Article
- Prediction, pain, and the power of context: toward a contemporary identity for the chiropractic profession.Chiropractic & manual therapies · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
introductionPersistent musculoskeletal (MSK) pain conditions are highly prevalent and economically burdensome. Although extensive research has explored various management strategies for these conditions, most interventions yield only modest effects. Recently, there has been increasing recognition of neuro-immune contributions in several persistent MSK pain conditions not traditionally associated with such influences. PURPOSE: The aim of this Masterclass is to provide an overview of some key neuro-immune factors that may contribute to persistent MSK pain whilst detailing both simple bedside and advanced novel methods to identify such neuro-immune contributions. It will also examine why an understanding of such contributions may be beneficial for the assessment and management of people with persistent MSK pain conditions. IMPLICATIONS: Understanding neuro-immune contributions to persistent MSK pain and how to identify them will help clinicians to i). consider the involvement of the nervous and immune systems when managing people with persistent MSK pain conditions, ii). better understand the use of both simple bedside tests and novel methods to identify such mechanisms and iii). consider how neuro-immune contributions may inform management strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.