ArticlePuerto Rico health sciences journal2025
Insights into Food Intake, Overall Diet Quality, and Stool Short-Chain Fatty Acids during Treatment for Rectal Cancer: A Pilot Study.
Article in Puerto Rico health sciences journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectiveTo describe food intake and overall diet quality during neoadjuvant concomitant chemotherapy and radiation therapy (nCRT) for rectal cancer. We also explored associations between Prime Diet Quality Score (PDQS) and short-chain fatty acid (SCFA) levels in stool at the end of nCRT in a subset of participants.
methodsThirty-two participants provided a 24-hour dietary recall, while 18 provided stool samples for SCFA analysis.
resultsThe reported intake of 11 healthy food groups (e.g., dark green vegetables, fish) was low (<50% of participants) before treatment, while 4 unhealthy food groups (e.g., processed meat, sugar-sweetened beverages) were high (>50%), both before and after treatment. Higher propionate levels were associated with higher PDQS values.
conclusionParticipants reported reduced dietary intake and diet quality during nCRT. Additional study is warranted to determine whether gut metabolites may mediate the impact of low diet quality.
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41401094PMC13075386What OpenQuestion holds
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